Pyogenic granuloma: An unrecognized cause of gastrointestinal bleeding

Susanne Van Eeden, G. Johan A Offerhaus, Folkert H. Morsink, Bastiaan P. Van Rees, Olivier R C Busch, Carel J M Van Noesel

Research output: Contribution to journalArticle

Abstract

Pyogenic granuloma is a lobular capillary hemangioma that mostly occurs on the skin, but it is also encountered on the mucosal surface of the oral cavity. Only a few cases in other parts of the digestive tract have been reported in Japanese patients. In this report, two Caucasian patients are described, who presented with gastrointestinal bleeding due to the presence of a pyogenic granuloma. One was located in the distal esophagus and could be treated with local excision and laser-photocoagulation therapy. The other one was located in the small intestine and was removed by surgical resection. Although extremely rare, pyogenic granuloma as a cause of gastrointestinal bleeding needs consideration. The lesion is benign, presumably reactive and can be adequately treated by excision or laser photocoagulation. Immunohistochemistry and/or polymerase chain reaction for herpesvirus 8 can reliably distinguish pyogenic granuloma from Kaposi's sarcoma, an important differential diagnosis.

Original languageEnglish (US)
Pages (from-to)590-593
Number of pages4
JournalVirchows Archiv
Volume444
Issue number6
StatePublished - Jun 2004
Externally publishedYes

Fingerprint

Pyogenic Granuloma
Hemorrhage
Light Coagulation
Kaposi's Sarcoma
Herpesviridae
Laser Therapy
Esophagus
Small Intestine
Mouth
Gastrointestinal Tract
Lasers
Differential Diagnosis
Immunohistochemistry
Polymerase Chain Reaction
Skin

Keywords

  • Esophagus
  • Gastrointestinal bleeding
  • HHV-8
  • Pyogenic granuloma
  • Small intestine

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Van Eeden, S., Offerhaus, G. J. A., Morsink, F. H., Van Rees, B. P., Busch, O. R. C., & Van Noesel, C. J. M. (2004). Pyogenic granuloma: An unrecognized cause of gastrointestinal bleeding. Virchows Archiv, 444(6), 590-593.

Pyogenic granuloma : An unrecognized cause of gastrointestinal bleeding. / Van Eeden, Susanne; Offerhaus, G. Johan A; Morsink, Folkert H.; Van Rees, Bastiaan P.; Busch, Olivier R C; Van Noesel, Carel J M.

In: Virchows Archiv, Vol. 444, No. 6, 06.2004, p. 590-593.

Research output: Contribution to journalArticle

Van Eeden, S, Offerhaus, GJA, Morsink, FH, Van Rees, BP, Busch, ORC & Van Noesel, CJM 2004, 'Pyogenic granuloma: An unrecognized cause of gastrointestinal bleeding', Virchows Archiv, vol. 444, no. 6, pp. 590-593.
Van Eeden S, Offerhaus GJA, Morsink FH, Van Rees BP, Busch ORC, Van Noesel CJM. Pyogenic granuloma: An unrecognized cause of gastrointestinal bleeding. Virchows Archiv. 2004 Jun;444(6):590-593.
Van Eeden, Susanne ; Offerhaus, G. Johan A ; Morsink, Folkert H. ; Van Rees, Bastiaan P. ; Busch, Olivier R C ; Van Noesel, Carel J M. / Pyogenic granuloma : An unrecognized cause of gastrointestinal bleeding. In: Virchows Archiv. 2004 ; Vol. 444, No. 6. pp. 590-593.
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