Putting patients at the center of kidney care transitions: PREPARE NOW, a cluster randomized controlled trial

J. A. Green, P. L. Ephraim, F. F. Hill-Briggs, T. Browne, T. S. Strigo, C. L. Hauer, R. A. Stametz, J. D. Darer, U. D. Patel, K. Lang-Lindsey, B. L. Bankes, S. A. Bolden, P. Danielson, S. Ruff, L. Schmidt, A. Swoboda, P. Woods, B. Vinson, D. Littlewood, G. JacksonJ. F. Pendergast, J. St. Clair Russell, K. Collins, E. Norfolk, I. D. Bucaloiu, S. Kethireddy, C. Collins, D. Davis, J. dePrisco, D. Malloy, Clarissa Diamantidis, S. Fulmer, J. Martin, D. Schatell, N. Tangri, A. Sees, C. Siegrist, J. Breed, A. Medley, E. Graboski, J. Billet, M. Hackenberg, D. Singer, S. Stewart, A. Alkon, N. A. Bhavsar, L. Lewis-Boyer, C. Martz, C. Yule, R. C. Greer, M. Saunders, B. Cameron, L. E. Boulware

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Care for patients transitioning from chronic kidney disease to kidney failure often falls short of meeting patients’ needs. The PREPARE NOW study is a cluster randomized controlled trial studying the effectiveness of a pragmatic health system intervention, ‘Patient Centered Kidney Transition Care,’ a multi-component health system intervention designed to improve patients’ preparation for kidney failure treatment. Patient-Centered Kidney Transition Care provides a suite of new electronic health information tools (including a disease registry and risk prediction tools) to help providers recognize patients in need of Kidney Transitions Care and focus their attention on patients’ values and treatment preferences. Patient-Centered Kidney Transition Care also adds a ‘Kidney Transitions Specialist’ to the nephrology health care team to facilitate patients’ self-management empowerment, shared-decision making, psychosocial support, care navigation, and health care team communication. The PREPARE NOW study is conducted among eight [8] outpatient nephrology clinics at Geisinger, a large integrated health system in rural Pennsylvania. Four randomly selected nephrology clinics employ the Patient Centered Kidney Transitions Care intervention while four clinics employ usual nephrology care. To assess intervention effectiveness, patient reported, biomedical, and health system outcomes are collected annually over a period of 36 months via telephone questionnaires and electronic health records. The PREPARE NOW Study may provide needed evidence on the effectiveness of patient-centered health system interventions to improve nephrology patients’ experiences, capabilities, and clinical outcomes, and it will guide the implementation of similar interventions elsewhere.

Original languageEnglish (US)
Pages (from-to)98-110
Number of pages13
JournalContemporary Clinical Trials
StatePublished - Oct 2018


  • Care navigation
  • Chronic kidney disease
  • Electronic health tools
  • Kidney failure
  • Self-management
  • Shared decision-making

ASJC Scopus subject areas

  • Pharmacology (medical)


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