Pulse wave velocity testing in the baltimore longitudinal study of aging

Melissa David, Omar Malti, Majd AlGhatrif, Jeanette Wright, Marco Canepa, James B. Strait

Research output: Contribution to journalArticlepeer-review


Carotid-femoral pulse wave velocity is considered the gold standard for measurements of central arterial stiffness obtained through noninvasive methods1. Subjects are placed in the supine position and allowed to rest quietly for at least 10 min prior to the start of the exam. The proper cuff size is selected and a blood pressure is obtained using an oscillometric device. Once a resting blood pressure has been obtained, pressure waveforms are acquired from the right femoral and right common carotid arteries. The system then automatically calculates the pulse transit time between these two sites (using the carotid artery as a surrogate for the descending aorta). Body surface measurements are used to determine the distance traveled by the pulse wave between the two sampling sites. This distance is then divided by the pulse transit time resulting in the pulse wave velocity. The measurements are performed in triplicate and the average is used for analysis.

Original languageEnglish (US)
Article numbere50817
JournalJournal of Visualized Experiments
Issue number84
StatePublished - Feb 7 2014
Externally publishedYes


  • Aging
  • Arterial stiffness
  • Cardiovascular
  • Carotid-femoral pulse
  • Issue 84
  • Medicine
  • Pulse wave analysis (PWA)
  • Pulse wave velocity (PWV)

ASJC Scopus subject areas

  • Neuroscience(all)
  • Chemical Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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