Pulse Therapy: Therapeutic Efficacy in the Treatment of Pyoderma Gangrenosum

Robert B. Johnson; Gerald Sylvan Lazarus

doi:10.1001/archderm.118.2.76

Pulse Therapy: Therapeutic Efficacy in the Treatment of Pyoderma Gangrenosum

Robert B. Johnson, Gerald Sylvan Lazarus

Research output: Contribution to journal › Article › peer-review

Abstract

Three patients with pyoderma gangrenosum were treated with suprapharmacologic doses of methylprednisolone sodium succinate using a five-day pulse therapy regimen. This therapy produced a dramatic remission with minimal side effects. The effects of pulse therapy are reviewed, and its role in severe steroid-responsive dermatoses is discussed. (Arch Dermatol 1982;118:76-84).

Original language	English (US)
Pages (from-to)	76-84
Number of pages	9
Journal	Archives of Dermatology
Volume	118
Issue number	2
DOIs	https://doi.org/10.1001/archderm.118.2.76
State	Published - Jan 1 1982
Externally published	Yes

ASJC Scopus subject areas

Dermatology

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abstract = "Three patients with pyoderma gangrenosum were treated with suprapharmacologic doses of methylprednisolone sodium succinate using a five-day pulse therapy regimen. This therapy produced a dramatic remission with minimal side effects. The effects of pulse therapy are reviewed, and its role in severe steroid-responsive dermatoses is discussed. (Arch Dermatol 1982;118:76-84).",

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