Pulmonary Venous Hypertension

Andrew Lerner, Jess Mandel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Pulmonary venous hypertension (PVH) develops secondary to any left-sided heart disease associated with increased left atrial pressures. The classic hemodynamic profile in PVH is an elevated pulmonary artery pressure associated with an elevated pulmonary capillary wedge pressure and left ventricular enddiastolic pressure. There are two basic mechanisms in the pathophysiology of the disease: a passive component and a reactive component. In the passive form, pulmonary hypertension is a reflection of the passive downstream trans mission of elevated left heart pressures into the pulmonary vascular system. In the reactive form, a dysregulation of vascular smooth muscle tone and structural remodeling occur in the pulmonary vascular leading to elevated pulmonary arterial pressures considered “out of proportion” to the degree of left-sided heart disease. The main objective in the evaluation of PVH is to differentiate it from other forms of pulmonary. The mainstay treatment of PVH is directed at the cardiac dysfunction, rather than targeting the elevated pulmonary artery pressures alone.

Original languageEnglish (US)
Title of host publicationPanVascular Medicine, Second Edition
PublisherSpringer Berlin Heidelberg
Pages4157-4168
Number of pages12
ISBN (Electronic)9783642370786
ISBN (Print)9783642370779
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Pulmonary Hypertension
Lung
Pressure
Pulmonary Artery
Blood Vessels
Heart Diseases
Pulmonary Wedge Pressure
Atrial Pressure
Ventricular Pressure
Vascular Smooth Muscle
Capillarity
Hemodynamics
Arterial Pressure
Muscle

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Lerner, A., & Mandel, J. (2015). Pulmonary Venous Hypertension. In PanVascular Medicine, Second Edition (pp. 4157-4168). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-37078-6_161

Pulmonary Venous Hypertension. / Lerner, Andrew; Mandel, Jess.

PanVascular Medicine, Second Edition. Springer Berlin Heidelberg, 2015. p. 4157-4168.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lerner, A & Mandel, J 2015, Pulmonary Venous Hypertension. in PanVascular Medicine, Second Edition. Springer Berlin Heidelberg, pp. 4157-4168. https://doi.org/10.1007/978-3-642-37078-6_161
Lerner A, Mandel J. Pulmonary Venous Hypertension. In PanVascular Medicine, Second Edition. Springer Berlin Heidelberg. 2015. p. 4157-4168 https://doi.org/10.1007/978-3-642-37078-6_161
Lerner, Andrew ; Mandel, Jess. / Pulmonary Venous Hypertension. PanVascular Medicine, Second Edition. Springer Berlin Heidelberg, 2015. pp. 4157-4168
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