TY - JOUR
T1 - Pulmonary Veno-occlusive Disease
T2 - Morphological Changes Suggesting a Viral Cause
AU - McDonnell, Peter J.
AU - Hutchins, Grover M.
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1981/8/7
Y1 - 1981/8/7
N2 - A 47-year-old man with a history of industrial exposure and interstitial lung disease was admitted for acute pulmonary decompensation. Clinical course was characterized by severe dyspnea at rest, fever, hypoxemia, and elevated pulmonary arterial pressures. At autopsy, pulmonary problems were explained by a selective veno-occlusive process. Associated with pulmonary phlebitis was cerebral vasculitis and lymph node enlargement with erythrophagocytosis suggesting underlying viral infection. Pulmonary veno-occlusive disease should be considered in cases of pulmonary fibrosis, pulmonary hypertension with cor pulmonale, and pulmonary edema and congestion with normal left atrial pressures. (JAMA 1981;246:667-671).
AB - A 47-year-old man with a history of industrial exposure and interstitial lung disease was admitted for acute pulmonary decompensation. Clinical course was characterized by severe dyspnea at rest, fever, hypoxemia, and elevated pulmonary arterial pressures. At autopsy, pulmonary problems were explained by a selective veno-occlusive process. Associated with pulmonary phlebitis was cerebral vasculitis and lymph node enlargement with erythrophagocytosis suggesting underlying viral infection. Pulmonary veno-occlusive disease should be considered in cases of pulmonary fibrosis, pulmonary hypertension with cor pulmonale, and pulmonary edema and congestion with normal left atrial pressures. (JAMA 1981;246:667-671).
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U2 - 10.1001/jama.1981.03320060069023
DO - 10.1001/jama.1981.03320060069023
M3 - Article
C2 - 7253118
AN - SCOPUS:0019822920
VL - 246
SP - 667
EP - 671
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
SN - 0098-7484
IS - 6
ER -