Pulmonary vascular responses to chronic hypoxia mediated by hypoxia-inducible factor 1

Research output: Contribution to journalArticle

Abstract

Hypoxia-inducible factor 1 (HIF-1) is a master regulator of oxygen homeostasis that controls transcriptional responses to hypoxia. HIF-1 plays critical roles both during development and in response to physiologic and pathophysiologic stimuli in the adult. Here, the involvement of HIF-1 in lung pathophysiology will be discussed.

Original languageEnglish (US)
Pages (from-to)68-70
Number of pages3
JournalProceedings of the American Thoracic Society
Volume2
Issue number1
DOIs
StatePublished - May 5 2005

Keywords

  • Gene expression
  • Oxygen sensing
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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