Pulmonary nodules: Sensitivity of maximum intensity projection versus that of volume rendering of 3D mul tidetector CT data

Philipp Peloschek, Johannes Sailer, Michael Weber, Christian J. Herold, Mathias Prokop, Cornelia Schaefer-Prokop

Research output: Contribution to journalArticle

Abstract

Purpose: To prospectively compare maximum intensity projection (MIP) and volume rendering (VR) of multidetector computed tomographic (CT) data for the detection of small intrapulmonary nodules. Materials and Methods: This institutional review board-approved prospective study included 20 oncology patients (eight women and 12 men; mean age, 56 years ± 16 [standard deviation]) who underwent clinically indicated standard-dose thoracic multidetector CT and provided informed consent. Transverse thin slabs of the chest (thickness, 7 mm; reconstruction increment, 3,5 mm) were created by using MIP and VR techniques to reconstruct CT data (collimation, 16 x 0.75 mm) and were reviewed in interactive cine mode. Mean, minimum, and maximum reading time per examination and per radiologist was documented. Three radiologists digitally annotated all nodules seen in a way that clearly determined their locations. The maximum number of nodules detected by the three observers and confirmed by consensus served as the reference standard. Descriptive statistics were calculated, with P <.05 indicating a significant difference. The Wilcoxon matched-pairs signed rank test and confidence intervals for differences between methods were used to compare the sensitivities of the two methods. Results: VR performed significantly better than MIP with regard to both detection rate (P <.001) and reporting time (P <.001). The superiority of VR was significant for all three observers and for nodules smaller than 11 mm in diameter and was pronounced for perihilar nodules (P = .023). Sensitivities achieved with VR ranged from 76.5% to 97.3%, depending on nodule size. Conclusion: VR is the superior reading method compared with MIP for the detection of small solid intrapulmonary nodules.

Original languageEnglish (US)
Pages (from-to)561-569
Number of pages9
JournalRadiology
Volume243
Issue number2
DOIs
StatePublished - May 2007
Externally publishedYes

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Lung
Reading
Thorax
Research Ethics Committees
Informed Consent
Prospective Studies
Confidence Intervals
Radiologists

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Peloschek, P., Sailer, J., Weber, M., Herold, C. J., Prokop, M., & Schaefer-Prokop, C. (2007). Pulmonary nodules: Sensitivity of maximum intensity projection versus that of volume rendering of 3D mul tidetector CT data. Radiology, 243(2), 561-569. https://doi.org/10.1148/radiol.2432052052

Pulmonary nodules : Sensitivity of maximum intensity projection versus that of volume rendering of 3D mul tidetector CT data. / Peloschek, Philipp; Sailer, Johannes; Weber, Michael; Herold, Christian J.; Prokop, Mathias; Schaefer-Prokop, Cornelia.

In: Radiology, Vol. 243, No. 2, 05.2007, p. 561-569.

Research output: Contribution to journalArticle

Peloschek, P, Sailer, J, Weber, M, Herold, CJ, Prokop, M & Schaefer-Prokop, C 2007, 'Pulmonary nodules: Sensitivity of maximum intensity projection versus that of volume rendering of 3D mul tidetector CT data', Radiology, vol. 243, no. 2, pp. 561-569. https://doi.org/10.1148/radiol.2432052052
Peloschek, Philipp ; Sailer, Johannes ; Weber, Michael ; Herold, Christian J. ; Prokop, Mathias ; Schaefer-Prokop, Cornelia. / Pulmonary nodules : Sensitivity of maximum intensity projection versus that of volume rendering of 3D mul tidetector CT data. In: Radiology. 2007 ; Vol. 243, No. 2. pp. 561-569.
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