TY - JOUR
T1 - Pulmonary Infections in Pregnancy
AU - Mathad, Jyoti S.
AU - Gupta, Amita
N1 - Funding Information:
JSM and AG are supported by the Eunice Shriver National Institute of Child Health and Development of the National Institutes of Health under award number R01HD081929 and by the Ujala Foundation (Newtown Square, PA). AG is also supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under award number U01AI069497. She is also supported through the Gilead Foundation, and the Wyncote Foundation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Publisher Copyright:
© Thieme Medical Publishers333 Seventh Avenue, New York, NY 10001, USA.
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Pregnant women experience physiological and immunological changes that increase the risk or severity of certain pulmonary infections. These changes also affect drug disposition, which impacts treatment choices. In this article, we review the available data on (1) the physiological and immunological changes that specifically impact tuberculosis, influenza, and varicella pneumonia; (2) active and latent tuberculosis management, including drug monitoring and maternal-infant outcomes; (3) the treatment and prevention of influenza; and (4) the diagnosis and management of varicella pneumonia. Clinical trials often exclude pregnant women, but there is a consensus that treating pregnant women for tuberculosis, influenza, and varicella pneumonia improves outcomes for both the woman and her child.
AB - Pregnant women experience physiological and immunological changes that increase the risk or severity of certain pulmonary infections. These changes also affect drug disposition, which impacts treatment choices. In this article, we review the available data on (1) the physiological and immunological changes that specifically impact tuberculosis, influenza, and varicella pneumonia; (2) active and latent tuberculosis management, including drug monitoring and maternal-infant outcomes; (3) the treatment and prevention of influenza; and (4) the diagnosis and management of varicella pneumonia. Clinical trials often exclude pregnant women, but there is a consensus that treating pregnant women for tuberculosis, influenza, and varicella pneumonia improves outcomes for both the woman and her child.
UR - http://www.scopus.com/inward/record.url?scp=85019607011&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019607011&partnerID=8YFLogxK
U2 - 10.1055/s-0037-1602375
DO - 10.1055/s-0037-1602375
M3 - Article
C2 - 28561248
AN - SCOPUS:85019607011
SN - 1069-3424
VL - 38
SP - 174
EP - 184
JO - Seminars in Respiratory and Critical Care Medicine
JF - Seminars in Respiratory and Critical Care Medicine
IS - 2
M1 - 01287
ER -