Pulmonary hypertension and mitral regurgitation in an infant with an anatomically normal mitral valve

Ryan Hoang, William Cohen, Shireen Mukadam, Pamela Combs, Tarek Husayni, Chawki El-Zein, Luca Vricella, Narutoshi Hibino

Research output: Contribution to journalArticlepeer-review

Abstract

A full-term, female presented on her date of birth with severe pulmonary hypertension (PH) and mitral regurgitation (MR), requiring veno-arterial extracorporeal membrane oxygenation. After the treatment, her PH and MR were resolved with no anatomic abnormality present. We propose a positive feedback loop of PH causing right ventricular dilation and interventricular septal shifts, worsening MR, and elevated left atrial, and potentially pulmonary, pressures.

Original languageEnglish (US)
Pages (from-to)476-478
Number of pages3
JournalCardiology in the young
Volume31
Issue number3
DOIs
StatePublished - Mar 2021
Externally publishedYes

Keywords

  • Mitral regurgitation
  • PPHN
  • feedback loop
  • pulmonary hypertension
  • septal geometry

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

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