Pulmonary function in insulin-dependent diabetes mellitus with limited joint mobility

B. M. Schnapf, R. A. Banks, J. H. Silverstein, A. L. Rosenbloom, S. E. Chesrown, G. M. Loughlin

Research output: Contribution to journalArticle

Abstract

Patients with insulin-dependent diabetes mellitus (IDDM) and limited joint mobility (LJM) were studied to determine if altered respiratory mechanics were another manifestation of a generalized disturbance in collagen metabolism. Lung volumes and maximal expiratory flow volume curves were measured in 23 patients with IDDM. Patients were divided into 2 groups: (1) 11 without LJM, and (2) 12 with severe LJM. The groups were matched for age, sex, and glycemic control but not for duration of IDDM. In patients with severe LJM, forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were significantly decreased (p <0.05). Total lung capacity (TLC), thoracic gas volume (TGV) at functional residual capacity (FRC) and residual volume (RV) were also significantly lower (p <0.05) in the severe LJM group. There was no evidence of air-flow obstruction in either group. Our results demonstrate an association between severe LJM and a significant decrease in lung volumes. This could be due to decreased lung compliance or restriction of chest wall expansion.

Original languageEnglish (US)
Pages (from-to)930-932
Number of pages3
JournalAmerican Review of Respiratory Disease
Volume130
Issue number5
StatePublished - 1984
Externally publishedYes

Fingerprint

Type 1 Diabetes Mellitus
Joints
Lung
Maximal Expiratory Flow-Volume Curves
Respiratory Mechanics
Lung Compliance
Total Lung Capacity
Functional Residual Capacity
Residual Volume
Vital Capacity
Forced Expiratory Volume
Thoracic Wall
Research Design
Collagen
Thorax
Gases
Air

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Schnapf, B. M., Banks, R. A., Silverstein, J. H., Rosenbloom, A. L., Chesrown, S. E., & Loughlin, G. M. (1984). Pulmonary function in insulin-dependent diabetes mellitus with limited joint mobility. American Review of Respiratory Disease, 130(5), 930-932.

Pulmonary function in insulin-dependent diabetes mellitus with limited joint mobility. / Schnapf, B. M.; Banks, R. A.; Silverstein, J. H.; Rosenbloom, A. L.; Chesrown, S. E.; Loughlin, G. M.

In: American Review of Respiratory Disease, Vol. 130, No. 5, 1984, p. 930-932.

Research output: Contribution to journalArticle

Schnapf, BM, Banks, RA, Silverstein, JH, Rosenbloom, AL, Chesrown, SE & Loughlin, GM 1984, 'Pulmonary function in insulin-dependent diabetes mellitus with limited joint mobility', American Review of Respiratory Disease, vol. 130, no. 5, pp. 930-932.
Schnapf BM, Banks RA, Silverstein JH, Rosenbloom AL, Chesrown SE, Loughlin GM. Pulmonary function in insulin-dependent diabetes mellitus with limited joint mobility. American Review of Respiratory Disease. 1984;130(5):930-932.
Schnapf, B. M. ; Banks, R. A. ; Silverstein, J. H. ; Rosenbloom, A. L. ; Chesrown, S. E. ; Loughlin, G. M. / Pulmonary function in insulin-dependent diabetes mellitus with limited joint mobility. In: American Review of Respiratory Disease. 1984 ; Vol. 130, No. 5. pp. 930-932.
@article{b330eeda972646c8961b7c0cb9edebbf,
title = "Pulmonary function in insulin-dependent diabetes mellitus with limited joint mobility",
abstract = "Patients with insulin-dependent diabetes mellitus (IDDM) and limited joint mobility (LJM) were studied to determine if altered respiratory mechanics were another manifestation of a generalized disturbance in collagen metabolism. Lung volumes and maximal expiratory flow volume curves were measured in 23 patients with IDDM. Patients were divided into 2 groups: (1) 11 without LJM, and (2) 12 with severe LJM. The groups were matched for age, sex, and glycemic control but not for duration of IDDM. In patients with severe LJM, forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were significantly decreased (p <0.05). Total lung capacity (TLC), thoracic gas volume (TGV) at functional residual capacity (FRC) and residual volume (RV) were also significantly lower (p <0.05) in the severe LJM group. There was no evidence of air-flow obstruction in either group. Our results demonstrate an association between severe LJM and a significant decrease in lung volumes. This could be due to decreased lung compliance or restriction of chest wall expansion.",
author = "Schnapf, {B. M.} and Banks, {R. A.} and Silverstein, {J. H.} and Rosenbloom, {A. L.} and Chesrown, {S. E.} and Loughlin, {G. M.}",
year = "1984",
language = "English (US)",
volume = "130",
pages = "930--932",
journal = "American Journal of Respiratory and Critical Care Medicine",
issn = "1073-449X",
publisher = "American Thoracic Society",
number = "5",

}

TY - JOUR

T1 - Pulmonary function in insulin-dependent diabetes mellitus with limited joint mobility

AU - Schnapf, B. M.

AU - Banks, R. A.

AU - Silverstein, J. H.

AU - Rosenbloom, A. L.

AU - Chesrown, S. E.

AU - Loughlin, G. M.

PY - 1984

Y1 - 1984

N2 - Patients with insulin-dependent diabetes mellitus (IDDM) and limited joint mobility (LJM) were studied to determine if altered respiratory mechanics were another manifestation of a generalized disturbance in collagen metabolism. Lung volumes and maximal expiratory flow volume curves were measured in 23 patients with IDDM. Patients were divided into 2 groups: (1) 11 without LJM, and (2) 12 with severe LJM. The groups were matched for age, sex, and glycemic control but not for duration of IDDM. In patients with severe LJM, forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were significantly decreased (p <0.05). Total lung capacity (TLC), thoracic gas volume (TGV) at functional residual capacity (FRC) and residual volume (RV) were also significantly lower (p <0.05) in the severe LJM group. There was no evidence of air-flow obstruction in either group. Our results demonstrate an association between severe LJM and a significant decrease in lung volumes. This could be due to decreased lung compliance or restriction of chest wall expansion.

AB - Patients with insulin-dependent diabetes mellitus (IDDM) and limited joint mobility (LJM) were studied to determine if altered respiratory mechanics were another manifestation of a generalized disturbance in collagen metabolism. Lung volumes and maximal expiratory flow volume curves were measured in 23 patients with IDDM. Patients were divided into 2 groups: (1) 11 without LJM, and (2) 12 with severe LJM. The groups were matched for age, sex, and glycemic control but not for duration of IDDM. In patients with severe LJM, forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were significantly decreased (p <0.05). Total lung capacity (TLC), thoracic gas volume (TGV) at functional residual capacity (FRC) and residual volume (RV) were also significantly lower (p <0.05) in the severe LJM group. There was no evidence of air-flow obstruction in either group. Our results demonstrate an association between severe LJM and a significant decrease in lung volumes. This could be due to decreased lung compliance or restriction of chest wall expansion.

UR - http://www.scopus.com/inward/record.url?scp=0021713569&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021713569&partnerID=8YFLogxK

M3 - Article

C2 - 6497171

AN - SCOPUS:0021713569

VL - 130

SP - 930

EP - 932

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

SN - 1073-449X

IS - 5

ER -