Pulmonary defense mechanisms and the interaction between viruses and bacteria in acute respiratory infections

G. J. Jakab

Research output: Contribution to journalReview articlepeer-review

Abstract

Pulmonary virus infections are known to predispose to bacterial infections in the lung. The mechanism by which the virus renders the pulmonary system more susceptible to bacterial infection is reviewed. The bacterial multiplication associated with virus infections is related to defects in in situ bactericidal (phagocytic) mechanisms of the lung. This phagocytic dysfunction is localized to the intracellular killing mechanism of the alveolar macrophage phagocytic process.

Original languageEnglish (US)
Pages (from-to)119-135
Number of pages17
JournalClinical Respiratory Physiology
Volume13
Issue number1
StatePublished - Dec 1 1977

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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