TY - JOUR
T1 - Pulmonary Complications of Pediatric Hematopoietic Cell Transplantation A National Institutes of Health Workshop Summary
AU - Tamburro, Robert F.
AU - Cooke, Kenneth R.
AU - Davies, Stella M.
AU - Goldfarb, Samuel
AU - Hagood, James S.
AU - Srinivasan, Ashok
AU - Steiner, Marie E.
AU - Stokes, Dennis
AU - DiFronzo, Nancy
AU - El-Kassar, Nahed
AU - Shelburne, Nonniekaye
AU - Natarajan, Aruna
N1 - Funding Information:
Supported by the National Heart, Lung, Blood Institute, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Cancer Institute, U.S. National Institutes of Health.
Publisher Copyright:
Copyright © 2021 by the American Thoracic Society
PY - 2021/3
Y1 - 2021/3
N2 - Approximately 2,500 pediatric hematopoietic cell transplants (HCTs), most of which are allogeneic, are performed annually in the United States for life-threatening malignant and nonmalignant conditions. Although HCT is undertaken with curative intent, post-HCT complications limit successful outcomes, with pulmonary dysfunction representing the leading cause of nonrelapse mortality. To better understand, predict, prevent, and/or treat pulmonary complications after HCT, a multidisciplinary group of 33 experts met in a 2-day National Institutes of Health Workshop to identify knowledge gaps and research strategies most likely to improve outcomes. This summary of Workshop deliberations outlines the consensus focus areas for future research.
AB - Approximately 2,500 pediatric hematopoietic cell transplants (HCTs), most of which are allogeneic, are performed annually in the United States for life-threatening malignant and nonmalignant conditions. Although HCT is undertaken with curative intent, post-HCT complications limit successful outcomes, with pulmonary dysfunction representing the leading cause of nonrelapse mortality. To better understand, predict, prevent, and/or treat pulmonary complications after HCT, a multidisciplinary group of 33 experts met in a 2-day National Institutes of Health Workshop to identify knowledge gaps and research strategies most likely to improve outcomes. This summary of Workshop deliberations outlines the consensus focus areas for future research.
KW - Acute respiratory distress syndrome
KW - Hematopoietic cell transplantation
KW - Pediatrics
KW - Pulmonary complications
KW - Respiratory failure
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U2 - 10.1513/AnnalsATS.202001-006OT
DO - 10.1513/AnnalsATS.202001-006OT
M3 - Article
C2 - 33058742
AN - SCOPUS:85101942386
SN - 2329-6933
VL - 18
SP - 381
EP - 394
JO - Annals of the American Thoracic Society
JF - Annals of the American Thoracic Society
IS - 3
ER -