Pulmonary artery measurements in pulmonary hypertension: The role of computed tomography

Abdelkader Mahammedi, Alexander Oshmyansky, Paul M Hassoun, David Ross Thiemann, Stanley S. Siegelman

Research output: Contribution to journalArticle

Abstract

PURPOSE: We studied the relationship between pulmonary artery diameter (PAD) as measured on computed tomography (CT) and pulmonary artery pressure (PAP) with the specific goal of assessing the reliability of various measurements on high-resolution chest CT as predictors of pulmonary hypertension (PH). MATERIALS AND METHODS: In a preliminary study we determined the method of measuring the main PAD (mPAD) that best correlated with PAP. Using this approach we measured mPAD on CT and correlated the data with PAP obtained from right heart catheterization in 298 patients with known PH and in 102 controls. Various metrics were analyzed for their specificity and sensitivity as screening measurements for PH. RESULTS: The mean PAD and mPAD/ascending aorta diameter (AAD) ratio were found to have the highest correlation with PAP (r=0.51 and 0.53, respectively; P29.5 mm was found to be 70.8% sensitive and 79.4% specific for PH, and an mPAD threshold >31.5 mm had a sensitivity and specificity of 52.0% and 90.2%, respectively. An mPAD/AAD ratio >1 was found to be 70.8% sensitive and 76.5% specific for PH. There was no significant correlation between mPAD and body surface area or age (r=0.04 and 0.07, respectively). A strong statistically significant difference (P

Original languageEnglish (US)
Pages (from-to)96-103
Number of pages8
JournalJournal of Thoracic Imaging
Volume28
Issue number2
DOIs
StatePublished - Mar 2013

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Pulmonary Hypertension
Pulmonary Artery
Tomography
Pressure
Aorta
Sensitivity and Specificity
Body Surface Area
Cardiac Catheterization
Thorax

Keywords

  • Computed tomography
  • Heart catheterization
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pulmonary and Respiratory Medicine

Cite this

Pulmonary artery measurements in pulmonary hypertension : The role of computed tomography. / Mahammedi, Abdelkader; Oshmyansky, Alexander; Hassoun, Paul M; Thiemann, David Ross; Siegelman, Stanley S.

In: Journal of Thoracic Imaging, Vol. 28, No. 2, 03.2013, p. 96-103.

Research output: Contribution to journalArticle

Mahammedi, Abdelkader ; Oshmyansky, Alexander ; Hassoun, Paul M ; Thiemann, David Ross ; Siegelman, Stanley S. / Pulmonary artery measurements in pulmonary hypertension : The role of computed tomography. In: Journal of Thoracic Imaging. 2013 ; Vol. 28, No. 2. pp. 96-103.
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