Abstract
Tumours are highly complex and contain multiple cell types. Cancer-associated fibroblasts are now shown to have a critical role in directly leading cancer cell invasion. This intercellular interaction relies on a mechanically active cadherin-based junction, and CAF-led invasion is demonstrated to require E-cadherin in the cancer cell.
Original language | English (US) |
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Pages (from-to) | 147-149 |
Number of pages | 3 |
Journal | Nature Cell Biology |
Volume | 19 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1 2017 |
ASJC Scopus subject areas
- Cell Biology