Pulling cells out of tumours

Research output: Contribution to journalShort survey

Abstract

Tumours are highly complex and contain multiple cell types. Cancer-associated fibroblasts are now shown to have a critical role in directly leading cancer cell invasion. This intercellular interaction relies on a mechanically active cadherin-based junction, and CAF-led invasion is demonstrated to require E-cadherin in the cancer cell.

Original languageEnglish (US)
Pages (from-to)147-149
Number of pages3
JournalNature Cell Biology
Volume19
Issue number3
DOIs
StatePublished - Mar 1 2017

ASJC Scopus subject areas

  • Cell Biology

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