Puberty in boys: correlation of plasma levels of gonadotropins (LH, FSH), androgens (testosterone, androstenedione, dehydroepiandrosterone and its sulfate), estrogens (estrone and estradiol) and progestins (progesterone and 17 hydroxyprogesterone)

P. A. Lee, C. J. Migeon

Research output: Contribution to journalArticle

Abstract

Mean serum concentration of dehydroepiandrosterone (DHA), DHA sulfate (DHAS), progesterone (P), 17 hydroxyprogesterone (17 OH P), estrone (E1), estradiol (E2), and androstenedione (A) were compared from 43 boys followed longitudinally for as long as 4 yr during puberty. These data were also compared with serum levels of LH, FSH, and testosterone. Elevation is recognized early in puberty for DHAS, late in puberty for P and A, and gradually throughout puberty for E1, 17 OH P, and DHA. When compared by age, the same general pattern is apparent with adult levels of E1 reached at age 12, DHAS and E2 by 13, and DHA, P, 17 OH P, and A not until after age 15. Significant elevations of DHA occurred with the onset of pubic hair and voice change; elevations of DHAS occurred with the onset of genital and axillary hair growth; and testosterone increased with the onset of genital and pubic hair growth and voice change.

Original languageEnglish (US)
Pages (from-to)556-562
Number of pages7
JournalJournal of Clinical Endocrinology and Metabolism
Volume41
Issue number3
StatePublished - 1975

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17-alpha-Hydroxyprogesterone
Dehydroepiandrosterone Sulfate
Dehydroepiandrosterone
Androstenedione
Estrone
Progestins
Puberty
Gonadotropins
Androgens
Progesterone
Testosterone
Estradiol
Estrogens
Hair
Plasmas
Growth
Serum

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

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title = "Puberty in boys: correlation of plasma levels of gonadotropins (LH, FSH), androgens (testosterone, androstenedione, dehydroepiandrosterone and its sulfate), estrogens (estrone and estradiol) and progestins (progesterone and 17 hydroxyprogesterone)",
abstract = "Mean serum concentration of dehydroepiandrosterone (DHA), DHA sulfate (DHAS), progesterone (P), 17 hydroxyprogesterone (17 OH P), estrone (E1), estradiol (E2), and androstenedione (A) were compared from 43 boys followed longitudinally for as long as 4 yr during puberty. These data were also compared with serum levels of LH, FSH, and testosterone. Elevation is recognized early in puberty for DHAS, late in puberty for P and A, and gradually throughout puberty for E1, 17 OH P, and DHA. When compared by age, the same general pattern is apparent with adult levels of E1 reached at age 12, DHAS and E2 by 13, and DHA, P, 17 OH P, and A not until after age 15. Significant elevations of DHA occurred with the onset of pubic hair and voice change; elevations of DHAS occurred with the onset of genital and axillary hair growth; and testosterone increased with the onset of genital and pubic hair growth and voice change.",
author = "Lee, {P. A.} and Migeon, {C. J.}",
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AU - Lee, P. A.

AU - Migeon, C. J.

PY - 1975

Y1 - 1975

N2 - Mean serum concentration of dehydroepiandrosterone (DHA), DHA sulfate (DHAS), progesterone (P), 17 hydroxyprogesterone (17 OH P), estrone (E1), estradiol (E2), and androstenedione (A) were compared from 43 boys followed longitudinally for as long as 4 yr during puberty. These data were also compared with serum levels of LH, FSH, and testosterone. Elevation is recognized early in puberty for DHAS, late in puberty for P and A, and gradually throughout puberty for E1, 17 OH P, and DHA. When compared by age, the same general pattern is apparent with adult levels of E1 reached at age 12, DHAS and E2 by 13, and DHA, P, 17 OH P, and A not until after age 15. Significant elevations of DHA occurred with the onset of pubic hair and voice change; elevations of DHAS occurred with the onset of genital and axillary hair growth; and testosterone increased with the onset of genital and pubic hair growth and voice change.

AB - Mean serum concentration of dehydroepiandrosterone (DHA), DHA sulfate (DHAS), progesterone (P), 17 hydroxyprogesterone (17 OH P), estrone (E1), estradiol (E2), and androstenedione (A) were compared from 43 boys followed longitudinally for as long as 4 yr during puberty. These data were also compared with serum levels of LH, FSH, and testosterone. Elevation is recognized early in puberty for DHAS, late in puberty for P and A, and gradually throughout puberty for E1, 17 OH P, and DHA. When compared by age, the same general pattern is apparent with adult levels of E1 reached at age 12, DHAS and E2 by 13, and DHA, P, 17 OH P, and A not until after age 15. Significant elevations of DHA occurred with the onset of pubic hair and voice change; elevations of DHAS occurred with the onset of genital and axillary hair growth; and testosterone increased with the onset of genital and pubic hair growth and voice change.

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