Psychosocial risk factors and the metabolic syndrome in elderly persons

Findings from the health, aging and body composition study

Nicole Vogelzangs, Aartjan T F Beekman, Stephen B. Kritchevsky, Anne B. Newman, Marco Pahor, Kristine Yaffe, Susan M. Rubin, Tamara B. Harris, Suzanne Satterfield, Eleanor Marie Simonsick, Brenda W J H Penninx

Research output: Contribution to journalArticle

Abstract

Background. Psychosocial factors have been associated with metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons. Methods. Participants were 2917 persons aged 70-79 years enrolled in the Health, Aging and Body Composition study. Depressive and anxiety symptoms, negative life events, and inadequate emotional support were assessed, and a summary psychosocial risk index was calculated. Metabolic syndrome was defined as three or more of the following criteria: abdominal obesity, high triglycerides, low high-density lipoprotein (HDL) cholesterol, high fasting glucose, and high blood pressure. Results. Negative life events and inadequate emotional support increased the odds of having metabolic syndrome after adjustment for demographic and lifestyle variables (odds ratio [OR] per life event = 1.13, 95% confidence interval [CI] = 1.05-1.22; OR = 1.35, 95% CI = 1.10-1.66, respectively). The relationship between depressive symptoms and metabolic syndrome was only found in white (OR per standard deviation [SD]= 1.11, 95% CI = 1.01-1.23), but not in black (OR per SD = 0.97, 95% CI = 0.86-1.11) persons. Anxiety symptoms were significantly associated with metabolic syndrome in men (OR per SD = 1.13, 95% CI = 1.00-1.28), but not in women (OR per SD = 0.98, 95% CI = 0.89-1.08). Moreover, a higher score on the psychosocial risk index was associated with an increased probability of having the metabolic syndrome (OR = 1.30, 95% CI = 1.12-1.52). Conclusions. In the elderly population, different psychosocial risk factors are associated with a higher prevalence of the metabolic syndrome. Whether reduction or better management of psychosocial risk factors can improve the metabolic profile remains to be demonstrated.

Original languageEnglish (US)
Pages (from-to)563-569
Number of pages7
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume62
Issue number5
StatePublished - May 2007
Externally publishedYes

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Body Composition
Odds Ratio
Confidence Intervals
Psychology
Health
Anxiety
Depression
Metabolome
Abdominal Obesity
LDL Cholesterol
HDL Cholesterol
Life Style
Fasting
Triglycerides
Cardiovascular Diseases
Cross-Sectional Studies
Demography
Hypertension
Glucose
Population

ASJC Scopus subject areas

  • Aging

Cite this

Vogelzangs, N., Beekman, A. T. F., Kritchevsky, S. B., Newman, A. B., Pahor, M., Yaffe, K., ... Penninx, B. W. J. H. (2007). Psychosocial risk factors and the metabolic syndrome in elderly persons: Findings from the health, aging and body composition study. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 62(5), 563-569.

Psychosocial risk factors and the metabolic syndrome in elderly persons : Findings from the health, aging and body composition study. / Vogelzangs, Nicole; Beekman, Aartjan T F; Kritchevsky, Stephen B.; Newman, Anne B.; Pahor, Marco; Yaffe, Kristine; Rubin, Susan M.; Harris, Tamara B.; Satterfield, Suzanne; Simonsick, Eleanor Marie; Penninx, Brenda W J H.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 62, No. 5, 05.2007, p. 563-569.

Research output: Contribution to journalArticle

Vogelzangs, N, Beekman, ATF, Kritchevsky, SB, Newman, AB, Pahor, M, Yaffe, K, Rubin, SM, Harris, TB, Satterfield, S, Simonsick, EM & Penninx, BWJH 2007, 'Psychosocial risk factors and the metabolic syndrome in elderly persons: Findings from the health, aging and body composition study', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 62, no. 5, pp. 563-569.
Vogelzangs, Nicole ; Beekman, Aartjan T F ; Kritchevsky, Stephen B. ; Newman, Anne B. ; Pahor, Marco ; Yaffe, Kristine ; Rubin, Susan M. ; Harris, Tamara B. ; Satterfield, Suzanne ; Simonsick, Eleanor Marie ; Penninx, Brenda W J H. / Psychosocial risk factors and the metabolic syndrome in elderly persons : Findings from the health, aging and body composition study. In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2007 ; Vol. 62, No. 5. pp. 563-569.
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abstract = "Background. Psychosocial factors have been associated with metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons. Methods. Participants were 2917 persons aged 70-79 years enrolled in the Health, Aging and Body Composition study. Depressive and anxiety symptoms, negative life events, and inadequate emotional support were assessed, and a summary psychosocial risk index was calculated. Metabolic syndrome was defined as three or more of the following criteria: abdominal obesity, high triglycerides, low high-density lipoprotein (HDL) cholesterol, high fasting glucose, and high blood pressure. Results. Negative life events and inadequate emotional support increased the odds of having metabolic syndrome after adjustment for demographic and lifestyle variables (odds ratio [OR] per life event = 1.13, 95{\%} confidence interval [CI] = 1.05-1.22; OR = 1.35, 95{\%} CI = 1.10-1.66, respectively). The relationship between depressive symptoms and metabolic syndrome was only found in white (OR per standard deviation [SD]= 1.11, 95{\%} CI = 1.01-1.23), but not in black (OR per SD = 0.97, 95{\%} CI = 0.86-1.11) persons. Anxiety symptoms were significantly associated with metabolic syndrome in men (OR per SD = 1.13, 95{\%} CI = 1.00-1.28), but not in women (OR per SD = 0.98, 95{\%} CI = 0.89-1.08). Moreover, a higher score on the psychosocial risk index was associated with an increased probability of having the metabolic syndrome (OR = 1.30, 95{\%} CI = 1.12-1.52). Conclusions. In the elderly population, different psychosocial risk factors are associated with a higher prevalence of the metabolic syndrome. Whether reduction or better management of psychosocial risk factors can improve the metabolic profile remains to be demonstrated.",
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T1 - Psychosocial risk factors and the metabolic syndrome in elderly persons

T2 - Findings from the health, aging and body composition study

AU - Vogelzangs, Nicole

AU - Beekman, Aartjan T F

AU - Kritchevsky, Stephen B.

AU - Newman, Anne B.

AU - Pahor, Marco

AU - Yaffe, Kristine

AU - Rubin, Susan M.

AU - Harris, Tamara B.

AU - Satterfield, Suzanne

AU - Simonsick, Eleanor Marie

AU - Penninx, Brenda W J H

PY - 2007/5

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N2 - Background. Psychosocial factors have been associated with metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons. Methods. Participants were 2917 persons aged 70-79 years enrolled in the Health, Aging and Body Composition study. Depressive and anxiety symptoms, negative life events, and inadequate emotional support were assessed, and a summary psychosocial risk index was calculated. Metabolic syndrome was defined as three or more of the following criteria: abdominal obesity, high triglycerides, low high-density lipoprotein (HDL) cholesterol, high fasting glucose, and high blood pressure. Results. Negative life events and inadequate emotional support increased the odds of having metabolic syndrome after adjustment for demographic and lifestyle variables (odds ratio [OR] per life event = 1.13, 95% confidence interval [CI] = 1.05-1.22; OR = 1.35, 95% CI = 1.10-1.66, respectively). The relationship between depressive symptoms and metabolic syndrome was only found in white (OR per standard deviation [SD]= 1.11, 95% CI = 1.01-1.23), but not in black (OR per SD = 0.97, 95% CI = 0.86-1.11) persons. Anxiety symptoms were significantly associated with metabolic syndrome in men (OR per SD = 1.13, 95% CI = 1.00-1.28), but not in women (OR per SD = 0.98, 95% CI = 0.89-1.08). Moreover, a higher score on the psychosocial risk index was associated with an increased probability of having the metabolic syndrome (OR = 1.30, 95% CI = 1.12-1.52). Conclusions. In the elderly population, different psychosocial risk factors are associated with a higher prevalence of the metabolic syndrome. Whether reduction or better management of psychosocial risk factors can improve the metabolic profile remains to be demonstrated.

AB - Background. Psychosocial factors have been associated with metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons. Methods. Participants were 2917 persons aged 70-79 years enrolled in the Health, Aging and Body Composition study. Depressive and anxiety symptoms, negative life events, and inadequate emotional support were assessed, and a summary psychosocial risk index was calculated. Metabolic syndrome was defined as three or more of the following criteria: abdominal obesity, high triglycerides, low high-density lipoprotein (HDL) cholesterol, high fasting glucose, and high blood pressure. Results. Negative life events and inadequate emotional support increased the odds of having metabolic syndrome after adjustment for demographic and lifestyle variables (odds ratio [OR] per life event = 1.13, 95% confidence interval [CI] = 1.05-1.22; OR = 1.35, 95% CI = 1.10-1.66, respectively). The relationship between depressive symptoms and metabolic syndrome was only found in white (OR per standard deviation [SD]= 1.11, 95% CI = 1.01-1.23), but not in black (OR per SD = 0.97, 95% CI = 0.86-1.11) persons. Anxiety symptoms were significantly associated with metabolic syndrome in men (OR per SD = 1.13, 95% CI = 1.00-1.28), but not in women (OR per SD = 0.98, 95% CI = 0.89-1.08). Moreover, a higher score on the psychosocial risk index was associated with an increased probability of having the metabolic syndrome (OR = 1.30, 95% CI = 1.12-1.52). Conclusions. In the elderly population, different psychosocial risk factors are associated with a higher prevalence of the metabolic syndrome. Whether reduction or better management of psychosocial risk factors can improve the metabolic profile remains to be demonstrated.

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