Psychosis secondary to infections

Sarah Reading, John T. Little

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Introduction This section focuses on selected infectious diseases that have been directly associated with neuropsychiatric syndromes, specifically those resulting in secondary psychosis. Secondary psychosis is a severe abnormality of thought content or form due to an identifiable medical or neurological condition that can have many manifestations (Cummings, 1985; 1988). Although there is no single area where brain injury will reproducibly induce psychosis, temporo-parietal regions, caudate nuclei, and cholinergic and dopaminergic tracts appear to be important substrates in many cases of psychosis (Gaudreau & Gagnon, 2005; Iyo, Sekine, & Mori, 2004; Seeman et al., 2005; Shaw et al., 2004). Definition and diagnostic criteria Using the nomenclature of the Diagnostic and Statistical Manual of Mental Disorders (DSM IV; American Psychiatric Association, 1994), secondary psychosis may be classified as Delirium Due to a General Medical Condition, Psychotic Disorder Due to a General Medical Condition, or Mood Disorder Due to a General Medical Condition, with Psychotic Features. Psychosis in delirium occurs only during the episode of delirium. Delirium is an acute syndrome secondary to a medical condition with disturbance in consciousness, attention, and cognition, and which may fluctuate over hours (American Psychiatric Association, 1994). The latter two diagnoses refer to psychosis due to a general medical or neurological condition in which either the psychosis or the mood symptoms predominate. In this chapter we shall focus on psychosis secondary to infectious causes.

Original languageEnglish (US)
Title of host publicationThe Spectrum of Psychotic Disorders
Subtitle of host publicationNeurobiology, Etiology and Pathogenesis
PublisherCambridge University Press
Number of pages21
ISBN (Electronic)9780511543784
ISBN (Print)0521850568, 9780521850568
StatePublished - Jan 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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