Psychopharmacologic Treatment of Schizophrenia in Adolescents and Children

Esther S. Lee; Hal Kronsberg; Robert L. Findling

doi:10.1016/j.chc.2019.08.009

Psychopharmacologic Treatment of Schizophrenia in Adolescents and Children

Esther S. Lee, Hal Kronsberg, Robert L. Findling

School of Medicine

Research output: Contribution to journal › Review article

Abstract

An increasing number of antipsychotic medications have demonstrated efficacy in randomized placebo-controlled trials in the treatment of children and adolescents with schizophrenia. This review summarizes and synthesizes relevant antipsychotic medication studies, with particular emphasis on second-generation agents, and discusses other clinical considerations that may influence medication selection. With the exception of clozapine demonstrating superior efficacy in the improvement of psychotic symptoms in treatment-resistant patients, many antipsychotic agents have been shown to be similarly efficacious, including first-generation medications. Consideration of the side-effect profile, which can differ substantially from medication to medication, is essential when choosing treatment options.

Original language	English (US)
Journal	Child and Adolescent Psychiatric Clinics of North America
DOIs	https://doi.org/10.1016/j.chc.2019.08.009
State	Accepted/In press - Jan 1 2019

Keywords

Adolescents
Antipsychotic medication
Antipsychotic side effects
Children
Psychopharmacology
Psychosis
Schizophrenia

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Psychiatry and Mental health

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Lee, E. S., Kronsberg, H., & Findling, R. L. (Accepted/In press). Psychopharmacologic Treatment of Schizophrenia in Adolescents and Children. Child and Adolescent Psychiatric Clinics of North America. https://doi.org/10.1016/j.chc.2019.08.009

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