Psychopathology in first-episode schizophrenia and antibodies to Toxoplasma gondii

S. Bachmann, J. Schröder, C. Bottmer, E. F. Torrey, Robert H Yolken

Research output: Contribution to journalArticle

Abstract

Objective: Environmental factors such as infectious agents may contribute to the psychopathology and aetiology of schizophrenia. Toxoplasma gondii (TG) is a candidate infectious agent as it is known to replicate within the human central nervous system and to alter behaviour in experimental animals. Method: The relationship between antibodies to TG and psychopathological symptoms was examined in 34 first-episode patients with schizophrenia. Results: Results of regression analyses revealed that symptoms on admission, predictors of outcome, age and family history of psychiatric disease influenced the levels of antibodies to TG. Conclusions: These results indicate that TG infections may play a role in the clinical manifestation of psychopathology in a subgroup of patients with schizophrenia.

Original languageEnglish (US)
Pages (from-to)87-90
Number of pages4
JournalPsychopathology
Volume38
Issue number2
DOIs
StatePublished - Mar 2005

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Toxoplasma
Psychopathology
Schizophrenia
Antibodies
Toxoplasmosis
Psychiatry
Central Nervous System
Regression Analysis

Keywords

  • Psychopathology
  • Schizophrenia, first episode
  • Toxoplasma gondii

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)

Cite this

Psychopathology in first-episode schizophrenia and antibodies to Toxoplasma gondii. / Bachmann, S.; Schröder, J.; Bottmer, C.; Torrey, E. F.; Yolken, Robert H.

In: Psychopathology, Vol. 38, No. 2, 03.2005, p. 87-90.

Research output: Contribution to journalArticle

Bachmann, S. ; Schröder, J. ; Bottmer, C. ; Torrey, E. F. ; Yolken, Robert H. / Psychopathology in first-episode schizophrenia and antibodies to Toxoplasma gondii. In: Psychopathology. 2005 ; Vol. 38, No. 2. pp. 87-90.
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