Purpose: Previous studies have linked depression and stressful life events in HIV disease with a more rapid decline in CD4 count and progression to AIDS. However, the short-term effect of psychological and physical distress on HIV-1 RNA levels in patients on successful HAART has not been well studied. Method: Ten asymptomatic HIV-infected adults with suppression of viremia to 50 copies/mL. Psychological distress and physical pain were not associated with episodes of detectable viremia. Conclusion: Using frequent monitoring of HIV-1 RNA levels and patient ratings of mood, stress, and pain, we found that psychological distress and physical pain had no short-term adverse impact on HIV-1 RNA levels in highly adherent patients with stable suppression of viremia on HAART.
- Viral load
ASJC Scopus subject areas