Pseudomembranous Colitis Caused by Clostridia

D. W. Burdon, J. D. Brown, R. H. George, Y. Arabi, J. Alexander-Williams, M. R.B. Keighley, John Bartlett, te Wen Chang, Marc Gurwith, Sherwood L. Gorbach, Andrew B. Onderdonk

Research output: Contribution to journalLetter

Abstract

To the Editor: We have reported findings* in agreement with those of Bartlett and his colleagues in the March 9 issue of the Journal implicating Clostridium difficile as the etiologic agent of pseudomembranous colitis. Our results differ in that we isolated multiple strains of Cl. difficile from the feces of patients, many of which were sensitive to clindamycin, probably because of our policy of avoiding the use of clindamycin in the isolation medium. Strains were differentiated on the basis of variations in the pattern of biochemical reactions and antibiotic susceptibility. Twenty-seven strains were isolated from eight patients, of which 10. . .

Original languageEnglish (US)
Pages (from-to)48-49
Number of pages2
JournalNew England Journal of Medicine
Volume299
Issue number1
DOIs
StatePublished - Jul 6 1978
Externally publishedYes

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Pseudomembranous Enterocolitis
Clostridium difficile
Clindamycin
Clostridium
Feces
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Burdon, D. W., Brown, J. D., George, R. H., Arabi, Y., Alexander-Williams, J., Keighley, M. R. B., ... Onderdonk, A. B. (1978). Pseudomembranous Colitis Caused by Clostridia. New England Journal of Medicine, 299(1), 48-49. https://doi.org/10.1056/NEJM197807062990117

Pseudomembranous Colitis Caused by Clostridia. / Burdon, D. W.; Brown, J. D.; George, R. H.; Arabi, Y.; Alexander-Williams, J.; Keighley, M. R.B.; Bartlett, John; Chang, te Wen; Gurwith, Marc; Gorbach, Sherwood L.; Onderdonk, Andrew B.

In: New England Journal of Medicine, Vol. 299, No. 1, 06.07.1978, p. 48-49.

Research output: Contribution to journalLetter

Burdon, DW, Brown, JD, George, RH, Arabi, Y, Alexander-Williams, J, Keighley, MRB, Bartlett, J, Chang, TW, Gurwith, M, Gorbach, SL & Onderdonk, AB 1978, 'Pseudomembranous Colitis Caused by Clostridia', New England Journal of Medicine, vol. 299, no. 1, pp. 48-49. https://doi.org/10.1056/NEJM197807062990117
Burdon DW, Brown JD, George RH, Arabi Y, Alexander-Williams J, Keighley MRB et al. Pseudomembranous Colitis Caused by Clostridia. New England Journal of Medicine. 1978 Jul 6;299(1):48-49. https://doi.org/10.1056/NEJM197807062990117
Burdon, D. W. ; Brown, J. D. ; George, R. H. ; Arabi, Y. ; Alexander-Williams, J. ; Keighley, M. R.B. ; Bartlett, John ; Chang, te Wen ; Gurwith, Marc ; Gorbach, Sherwood L. ; Onderdonk, Andrew B. / Pseudomembranous Colitis Caused by Clostridia. In: New England Journal of Medicine. 1978 ; Vol. 299, No. 1. pp. 48-49.
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