TY - JOUR
T1 - Provider performance and facility readiness for managing infections in young infants in primary care facilities in rural Bangladesh
AU - Applegate, Jennifer A.
AU - Ahmed, Salahuddin
AU - Harrison, Meagan
AU - Callaghan, Jennifer
AU - Mousumi, Mahfuza
AU - Begum, Nazma
AU - Moin, Mamun Ibne
AU - Joarder, Taufique
AU - Ahmed, Sabbir
AU - George, Joby
AU - Mitra, Dipak K.
AU - Nawshad Uddin Ahmed, A. S.M.
AU - Shahidullah, Mohammod
AU - Baqui, Abdullah H.
N1 - Funding Information:
AB received support for this study from the United States Agency for International Development (USAID) through JHU’s Health Research Challenge for Impact (grant number GHS-A00-0900004-00). The contents are the responsibilities of the authors and do not necessarily reflect the views of USAID, the United States Government and/or the decisions, policy, or views of their respective organizations.
Publisher Copyright:
© 2020 World Health Organization. Licensee Public Library of Science. This is an open access article distributed under the Creative Commons Attribution IGO License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/3.0/igo/.
PY - 2020/4
Y1 - 2020/4
N2 - Background Neonatal infections remain a leading cause of newborn deaths globally. In 2015, WHO issued guidelines for managing possible serious bacterial infection (PSBI) in young infants (0–59 days) using simplified antibiotic regimens when compliance with hospital referral is not feasible. Bangladesh was one of the first countries to adopt WHO’s guidelines for implementation. We report results of an implementation research study that assessed facility readiness and provider performance in three rural sub-districts of Bangladesh during August 2015-August 2016. Methods This study took place in 19 primary health centers. Facility readiness was assessed using checklists completed by study staff at three time points. To assess provider performance, we extracted data for all infection cases from facility registers and compared providers’ diagnosis and treatment against the guidelines. We plotted classification and dosage errors across the study period and superimposed a locally weighted smoothed (LOWESS) curve to analyze changes in performance over time. Focus group discussions (N = 2) and in-depth interviews (N = 28) with providers were conducted to identify barriers and facilitators for facility readiness and provider performance. Results At baseline, none of the facilities had adequate supply of antibiotics. During the 10-month period, 606 sick infants with signs of infection presented at the study facilities. Classification errors were identified in 14.9% (N = 90/606) of records. For infants receiving the first dose(s) of antibiotic treatment (N = 551), dosage errors were identified in 22.9% (N = 126/551) of the records. Distribution of errors varied by facility (35.7% [IQR: 24.7–57.4%]) and infection severity. Errors were highest at the beginning of the study period and decreased over time. Qualitative data suggest errors in early implementation were due to changes in providers’ assessment and treatment practices, including confusion about classifying an infant with multiple signs of infection, and some providers’ concerns about the efficacy of simplified antibiotic regimens. Conclusions Strategies to monitor early performance and targeted supports are important for enhancing implementation fidelity when introducing complex guidelines in new settings. Future research should examine providers’ assessment of effectiveness of simplified treatment and address misconceptions about superiority of broader spectrum antibiotics for treating community-acquired neonatal infections in this context.
AB - Background Neonatal infections remain a leading cause of newborn deaths globally. In 2015, WHO issued guidelines for managing possible serious bacterial infection (PSBI) in young infants (0–59 days) using simplified antibiotic regimens when compliance with hospital referral is not feasible. Bangladesh was one of the first countries to adopt WHO’s guidelines for implementation. We report results of an implementation research study that assessed facility readiness and provider performance in three rural sub-districts of Bangladesh during August 2015-August 2016. Methods This study took place in 19 primary health centers. Facility readiness was assessed using checklists completed by study staff at three time points. To assess provider performance, we extracted data for all infection cases from facility registers and compared providers’ diagnosis and treatment against the guidelines. We plotted classification and dosage errors across the study period and superimposed a locally weighted smoothed (LOWESS) curve to analyze changes in performance over time. Focus group discussions (N = 2) and in-depth interviews (N = 28) with providers were conducted to identify barriers and facilitators for facility readiness and provider performance. Results At baseline, none of the facilities had adequate supply of antibiotics. During the 10-month period, 606 sick infants with signs of infection presented at the study facilities. Classification errors were identified in 14.9% (N = 90/606) of records. For infants receiving the first dose(s) of antibiotic treatment (N = 551), dosage errors were identified in 22.9% (N = 126/551) of the records. Distribution of errors varied by facility (35.7% [IQR: 24.7–57.4%]) and infection severity. Errors were highest at the beginning of the study period and decreased over time. Qualitative data suggest errors in early implementation were due to changes in providers’ assessment and treatment practices, including confusion about classifying an infant with multiple signs of infection, and some providers’ concerns about the efficacy of simplified antibiotic regimens. Conclusions Strategies to monitor early performance and targeted supports are important for enhancing implementation fidelity when introducing complex guidelines in new settings. Future research should examine providers’ assessment of effectiveness of simplified treatment and address misconceptions about superiority of broader spectrum antibiotics for treating community-acquired neonatal infections in this context.
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U2 - 10.1371/journal.pone.0229988
DO - 10.1371/journal.pone.0229988
M3 - Article
C2 - 32320993
AN - SCOPUS:85083731664
VL - 15
JO - PLoS One
JF - PLoS One
SN - 1932-6203
IS - 4
M1 - e0229988
ER -