Protocols for lung protective ventilation

Research output: Contribution to journalReview articlepeer-review


Protocols have a well-established role in clinical research and are increasingly being used to direct routine clinical care. In this article, we review the differing goals of research and clinical protocols and outline the similar process for their development. We use the mechanical ventilation protocol of the ARDS Network trial comparing small with traditional tidal volumes as an example. As a starting point for debate, we also suggest guiding principles and specific components of a protocol for high-frequency oscillatory ventilation.

Original languageEnglish (US)
Pages (from-to)S223-S227
JournalCritical care medicine
Issue number3 SUPPL.
StatePublished - Mar 1 2005


  • Acute respiratory distress syndrome
  • Clinical research
  • Clinical trials
  • Decision support
  • High-frequency oscillatory ventilation
  • Lung-protective ventilation
  • Mechanical ventilation
  • Process of care
  • Protocols
  • Ventilator-induced lung injury

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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