Abstract
Protocols have a well-established role in clinical research and are increasingly being used to direct routine clinical care. In this article, we review the differing goals of research and clinical protocols and outline the similar process for their development. We use the mechanical ventilation protocol of the ARDS Network trial comparing small with traditional tidal volumes as an example. As a starting point for debate, we also suggest guiding principles and specific components of a protocol for high-frequency oscillatory ventilation.
| Original language | English (US) |
|---|---|
| Journal | Critical Care Medicine |
| Volume | 33 |
| Issue number | 3 SUPPL. |
| DOIs | |
| State | Published - Mar 2005 |
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Keywords
- Acute respiratory distress syndrome
- Clinical research
- Clinical trials
- Decision support
- High-frequency oscillatory ventilation
- Lung-protective ventilation
- Mechanical ventilation
- Process of care
- Protocols
- Ventilator-induced lung injury
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine
Cite this
Protocols for lung protective ventilation. / Fessler, Henry Eric; Brower, Roy G.
In: Critical Care Medicine, Vol. 33, No. 3 SUPPL., 03.2005.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Protocols for lung protective ventilation
AU - Fessler, Henry Eric
AU - Brower, Roy G
PY - 2005/3
Y1 - 2005/3
N2 - Protocols have a well-established role in clinical research and are increasingly being used to direct routine clinical care. In this article, we review the differing goals of research and clinical protocols and outline the similar process for their development. We use the mechanical ventilation protocol of the ARDS Network trial comparing small with traditional tidal volumes as an example. As a starting point for debate, we also suggest guiding principles and specific components of a protocol for high-frequency oscillatory ventilation.
AB - Protocols have a well-established role in clinical research and are increasingly being used to direct routine clinical care. In this article, we review the differing goals of research and clinical protocols and outline the similar process for their development. We use the mechanical ventilation protocol of the ARDS Network trial comparing small with traditional tidal volumes as an example. As a starting point for debate, we also suggest guiding principles and specific components of a protocol for high-frequency oscillatory ventilation.
KW - Acute respiratory distress syndrome
KW - Clinical research
KW - Clinical trials
KW - Decision support
KW - High-frequency oscillatory ventilation
KW - Lung-protective ventilation
KW - Mechanical ventilation
KW - Process of care
KW - Protocols
KW - Ventilator-induced lung injury
UR - http://www.scopus.com/inward/record.url?scp=14944372530&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=14944372530&partnerID=8YFLogxK
U2 - 10.1097/01.CCM.0000155919.53727.D5
DO - 10.1097/01.CCM.0000155919.53727.D5
M3 - Article
VL - 33
JO - Critical Care Medicine
JF - Critical Care Medicine
SN - 0090-3493
IS - 3 SUPPL.
ER -