Abstract
Protocols have a well-established role in clinical research and are increasingly being used to direct routine clinical care. In this article, we review the differing goals of research and clinical protocols and outline the similar process for their development. We use the mechanical ventilation protocol of the ARDS Network trial comparing small with traditional tidal volumes as an example. As a starting point for debate, we also suggest guiding principles and specific components of a protocol for high-frequency oscillatory ventilation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | S223-S227 |
| Journal | Critical care medicine |
| Volume | 33 |
| Issue number | 3 SUPPL. |
| DOIs | |
| State | Published - Mar 1 2005 |
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Keywords
- Acute respiratory distress syndrome
- Clinical research
- Clinical trials
- Decision support
- High-frequency oscillatory ventilation
- Lung-protective ventilation
- Mechanical ventilation
- Process of care
- Protocols
- Ventilator-induced lung injury
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine
Cite this
Fessler, H. E., & Brower, R. G. (2005). Protocols for lung protective ventilation. Critical care medicine, 33(3 SUPPL.), S223-S227. https://doi.org/10.1097/01.CCM.0000155919.53727.D5