Proteolytic enzymes in salivary extravasation mucoceles.

M. Azuma, T. Tamatani, K. Fukui, T. Yuki, Mohammad Hoque, H. Yoshida, M. Sato

Research output: Contribution to journalArticle

Abstract

We examined the content of type IV collagenases and plasminogen activators (PAs) in luminal fluid of four extravasation mucoceles by means of gelatin or casein zymography. Immunohistochemical staining for type IV collagenases and PAs was performed to identify the possible source of these enzymes. The luminal fluid examined by gelatin zymography showed a high level of type IV collagenases compared with saliva from Wharton's duct. PAs were detected in only one of the cases by casein zymography, and none was detected in the saliva. By immunohistochemical staining, type IV collagenases and PAs were detected in duct and myoepithelial cells of the adjacent salivary gland and in macrophages and fibroblasts of the cyst wall. The results suggest that proteolytic enzymes are involved in the pathogenesis of mucoceles.

Original languageEnglish (US)
Pages (from-to)299-302
Number of pages4
JournalJournal of Oral Pathology and Medicine
Volume24
Issue number7
StatePublished - Aug 1995
Externally publishedYes

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Mucocele
Plasminogen Activators
Collagenases
Peptide Hydrolases
Gelatin
Caseins
Saliva
Salivary Ducts
Staining and Labeling
Salivary Glands
Cysts
Fibroblasts
Macrophages
Enzymes

ASJC Scopus subject areas

  • Cancer Research
  • Pathology and Forensic Medicine
  • Dentistry(all)

Cite this

Azuma, M., Tamatani, T., Fukui, K., Yuki, T., Hoque, M., Yoshida, H., & Sato, M. (1995). Proteolytic enzymes in salivary extravasation mucoceles. Journal of Oral Pathology and Medicine, 24(7), 299-302.

Proteolytic enzymes in salivary extravasation mucoceles. / Azuma, M.; Tamatani, T.; Fukui, K.; Yuki, T.; Hoque, Mohammad; Yoshida, H.; Sato, M.

In: Journal of Oral Pathology and Medicine, Vol. 24, No. 7, 08.1995, p. 299-302.

Research output: Contribution to journalArticle

Azuma, M, Tamatani, T, Fukui, K, Yuki, T, Hoque, M, Yoshida, H & Sato, M 1995, 'Proteolytic enzymes in salivary extravasation mucoceles.', Journal of Oral Pathology and Medicine, vol. 24, no. 7, pp. 299-302.
Azuma M, Tamatani T, Fukui K, Yuki T, Hoque M, Yoshida H et al. Proteolytic enzymes in salivary extravasation mucoceles. Journal of Oral Pathology and Medicine. 1995 Aug;24(7):299-302.
Azuma, M. ; Tamatani, T. ; Fukui, K. ; Yuki, T. ; Hoque, Mohammad ; Yoshida, H. ; Sato, M. / Proteolytic enzymes in salivary extravasation mucoceles. In: Journal of Oral Pathology and Medicine. 1995 ; Vol. 24, No. 7. pp. 299-302.
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