Protein translocation: Is Hsp70 pulling my chain?

Robert E. Jensen; Arthur E. Johnson

doi:10.1016/S0960-9822(00)80012-3

Protein translocation: Is Hsp70 pulling my chain?

Robert E. Jensen, Arthur E. Johnson

School of Medicine

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Hsp70 proteins in the lumen of the endoplasmic reticulum and in the mitochondrial matrix are thought to drive the translocation of proteins into each organelle. Recent experiments aimed at distinguishing between two models for Hsp70 function appear to reach opposite conclusions.

Original language	English (US)
Pages (from-to)	R779-R782
Journal	Current Biology
Volume	9
Issue number	20
DOIs	https://doi.org/10.1016/S0960-9822(00)80012-3
State	Published - Oct 21 1999

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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title = "Protein translocation: Is Hsp70 pulling my chain?",

abstract = "Hsp70 proteins in the lumen of the endoplasmic reticulum and in the mitochondrial matrix are thought to drive the translocation of proteins into each organelle. Recent experiments aimed at distinguishing between two models for Hsp70 function appear to reach opposite conclusions.",

author = "Jensen, {Robert E.} and Johnson, {Arthur E.}",

note = "Funding Information: We thank Oliver Kerscher for his creative artwork in the figures. We also thank Carolyn Machamer, Hiromi Sesaki, Alison Davis, Naresh Sepuri for comments on the manuscript. We thank the support of United States Public Health Service grants RO1-GM46803 to R.E.J. and RO1-GM26494 to A.E.J, and the Robert A. Welch Foundation (A.E.J.). ",

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AU - Jensen, Robert E.

AU - Johnson, Arthur E.

N1 - Funding Information: We thank Oliver Kerscher for his creative artwork in the figures. We also thank Carolyn Machamer, Hiromi Sesaki, Alison Davis, Naresh Sepuri for comments on the manuscript. We thank the support of United States Public Health Service grants RO1-GM46803 to R.E.J. and RO1-GM26494 to A.E.J, and the Robert A. Welch Foundation (A.E.J.).

PY - 1999/10/21

Y1 - 1999/10/21

N2 - Hsp70 proteins in the lumen of the endoplasmic reticulum and in the mitochondrial matrix are thought to drive the translocation of proteins into each organelle. Recent experiments aimed at distinguishing between two models for Hsp70 function appear to reach opposite conclusions.

AB - Hsp70 proteins in the lumen of the endoplasmic reticulum and in the mitochondrial matrix are thought to drive the translocation of proteins into each organelle. Recent experiments aimed at distinguishing between two models for Hsp70 function appear to reach opposite conclusions.

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Protein translocation: Is Hsp70 pulling my chain?

Abstract

ASJC Scopus subject areas

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