Protein arrays and microarrays

Heng Zhu, Michael Snyder

Research output: Contribution to journalReview articlepeer-review

358 Scopus citations

Abstract

In the past, studies of protein activities have focused on studying a single protein at a time, which is often time-consuming and expensive. Recently, with the sequencing of entire genomes, large-scale proteome analysis has begun. Arrays of proteins have been used for the determination of subcellular localization, analysis of protein-protein interactions and biochemical analysis of protein function. New protein-microarray technologies have been introduced that enable the high-throughput analysis of protein activities. These have the potential to revolutionize the analysis of entire proteomes.

Original languageEnglish (US)
Pages (from-to)40-45
Number of pages6
JournalCurrent Opinion in Chemical Biology
Volume5
Issue number1
DOIs
StatePublished - Feb 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

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