Protective CD8+ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression

Alexandre Morrot; Ian A. Cockburn; Michael Overstreet; Dolores Rodríguez; Fidel Zavala

doi:10.1128/IAI.74.4.2495-2497.2006

Protective CD8⁺ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression

Alexandre Morrot, Ian A. Cockburn, Michael Overstreet, Dolores Rodríguez, Fidel Zavala

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

CD8⁺ T cells induced by Plasmodium yoelii sporozoites develop into protective memory cells without undergoing changes in interleukin-7 receptor α (IL-7Rα) expression, differing from the development of memory CD8⁺ T cells against viruses, which is associated with enhanced IL-7Rα expression. This suggests a microbe-dependent diversity in the signals determining the development of memory populations.

Original language	English (US)
Pages (from-to)	2495-2497
Number of pages	3
Journal	Infection and immunity
Volume	74
Issue number	4
DOIs	https://doi.org/10.1128/IAI.74.4.2495-2497.2006
State	Published - Apr 2006

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

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10.1128/IAI.74.4.2495-2497.2006

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abstract = "CD8+ T cells induced by Plasmodium yoelii sporozoites develop into protective memory cells without undergoing changes in interleukin-7 receptor α (IL-7Rα) expression, differing from the development of memory CD8+ T cells against viruses, which is associated with enhanced IL-7Rα expression. This suggests a microbe-dependent diversity in the signals determining the development of memory populations.",

author = "Alexandre Morrot and Cockburn, {Ian A.} and Michael Overstreet and Dolores Rodr{\'i}guez and Fidel Zavala",

year = "2006",

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AU - Morrot, Alexandre

AU - Cockburn, Ian A.

AU - Overstreet, Michael

AU - Rodríguez, Dolores

AU - Zavala, Fidel

PY - 2006/4

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AB - CD8+ T cells induced by Plasmodium yoelii sporozoites develop into protective memory cells without undergoing changes in interleukin-7 receptor α (IL-7Rα) expression, differing from the development of memory CD8+ T cells against viruses, which is associated with enhanced IL-7Rα expression. This suggests a microbe-dependent diversity in the signals determining the development of memory populations.

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Protective CD8⁺ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression

Abstract

ASJC Scopus subject areas

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