Protective CD8+ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression

Alexandre Morrot; Ian A. Cockburn; Michael Overstreet; Dolores Rodríguez; Fidel Zavala

doi:10.1128/IAI.74.4.2495-2497.2006

Protective CD8⁺ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression

Alexandre Morrot, Ian A. Cockburn, Michael Overstreet, Dolores Rodríguez, Fidel Zavala

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

CD8⁺ T cells induced by Plasmodium yoelii sporozoites develop into protective memory cells without undergoing changes in interleukin-7 receptor α (IL-7Rα) expression, differing from the development of memory CD8⁺ T cells against viruses, which is associated with enhanced IL-7Rα expression. This suggests a microbe-dependent diversity in the signals determining the development of memory populations.

Original language	English (US)
Pages (from-to)	2495-2497
Number of pages	3
Journal	Infection and immunity
Volume	74
Issue number	4
DOIs	https://doi.org/10.1128/IAI.74.4.2495-2497.2006
State	Published - Apr 2006

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

Access to Document

10.1128/IAI.74.4.2495-2497.2006

Fingerprint Dive into the research topics of 'Protective CD8<sup>+</sup> T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression'. Together they form a unique fingerprint.

Cite this

@article{78e84b9496ad473c82a9b34134f1d611,

title = "Protective CD8+ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression",

abstract = "CD8+ T cells induced by Plasmodium yoelii sporozoites develop into protective memory cells without undergoing changes in interleukin-7 receptor α (IL-7Rα) expression, differing from the development of memory CD8+ T cells against viruses, which is associated with enhanced IL-7Rα expression. This suggests a microbe-dependent diversity in the signals determining the development of memory populations.",

author = "Alexandre Morrot and Cockburn, {Ian A.} and Michael Overstreet and Dolores Rodr{\'i}guez and Fidel Zavala",

year = "2006",

month = apr,

doi = "10.1128/IAI.74.4.2495-2497.2006",

language = "English (US)",

volume = "74",

pages = "2495--2497",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "4",

}

TY - JOUR

T1 - Protective CD8+ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression

AU - Morrot, Alexandre

AU - Cockburn, Ian A.

AU - Overstreet, Michael

AU - Rodríguez, Dolores

AU - Zavala, Fidel

PY - 2006/4

Y1 - 2006/4

N2 - CD8+ T cells induced by Plasmodium yoelii sporozoites develop into protective memory cells without undergoing changes in interleukin-7 receptor α (IL-7Rα) expression, differing from the development of memory CD8+ T cells against viruses, which is associated with enhanced IL-7Rα expression. This suggests a microbe-dependent diversity in the signals determining the development of memory populations.

AB - CD8+ T cells induced by Plasmodium yoelii sporozoites develop into protective memory cells without undergoing changes in interleukin-7 receptor α (IL-7Rα) expression, differing from the development of memory CD8+ T cells against viruses, which is associated with enhanced IL-7Rα expression. This suggests a microbe-dependent diversity in the signals determining the development of memory populations.

UR - http://www.scopus.com/inward/record.url?scp=33645510077&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645510077&partnerID=8YFLogxK

U2 - 10.1128/IAI.74.4.2495-2497.2006

DO - 10.1128/IAI.74.4.2495-2497.2006

M3 - Article

C2 - 16552087

AN - SCOPUS:33645510077

VL - 74

SP - 2495

EP - 2497

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 4