Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain

Luke E. Osborn, Andrei Dragomir, Joseph L. Betthauser, Christopher L. Hunt, Harrison H. Nguyen, Rahul R. Kaliki, Nitish V Thakor

Research output: Contribution to journalArticle

Abstract

The human body is a template for many state-of-the-art prosthetic devices and sensors. Perceptions of touch and pain are fundamental components of our daily lives that convey valuable information about our environment while also providing an element of protection from damage to our bodies. Advances in prosthesis designs and control mechanisms can aid an amputee's ability to regain lost function but often lack meaningful tactile feedback or perception. Through transcutaneous electrical nerve stimulation (TENS) with an amputee, wediscovered and quantified stimulation parameters to elicit innocuous (nonpainful) and noxious (painful) tactile perceptions in the phantom hand. Electroencephalography (EEG) activity in somatosensory regions confirms phantom hand activation during stimulation. We invented a multilayered electronic dermis (e-dermis) with properties based on the behavior of mechanoreceptors and nociceptors to provide neuromorphic tactile information to an amputee. Our biologically inspired e-dermis enables a prosthesis and its user to perceive a continuous spectrum from innocuous to noxious touch through a neuromorphic interface that produces receptor-like spiking neural activity. In a pain detection task (PDT), we show the ability of the prosthesis and amputee to differentiate nonpainful or painful tactile stimuli using sensory feedback and a pain reflex feedback control system. In this work, an amputee can use perceptions of touch and pain to discriminate object curvature, including sharpness. This work demonstrates possibilities for creating a more natural sensation spanning a range of tactile stimuli for prosthetic hands.

Original languageEnglish (US)
Article numbereaat3818
JournalScience Robotics
Volume3
Issue number19
DOIs
StatePublished - Jun 27 2018

Fingerprint

Pain
Electronics
Prosthetics
Sensory feedback
Phantom
Regain
Electroencephalography
Feedback control
Chemical activation
Continuous Spectrum
Feedback
Control systems
Sharpness
Feedback Systems
Nerve
Differentiate
Receptor
Feedback Control
Sensors
Template

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computer Science Applications
  • Mechanical Engineering
  • Control and Optimization

Cite this

Osborn, L. E., Dragomir, A., Betthauser, J. L., Hunt, C. L., Nguyen, H. H., Kaliki, R. R., & Thakor, N. V. (2018). Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain. Science Robotics, 3(19), [eaat3818]. https://doi.org/10.1126/scirobotics.aat3818

Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain. / Osborn, Luke E.; Dragomir, Andrei; Betthauser, Joseph L.; Hunt, Christopher L.; Nguyen, Harrison H.; Kaliki, Rahul R.; Thakor, Nitish V.

In: Science Robotics, Vol. 3, No. 19, eaat3818, 27.06.2018.

Research output: Contribution to journalArticle

Osborn, LE, Dragomir, A, Betthauser, JL, Hunt, CL, Nguyen, HH, Kaliki, RR & Thakor, NV 2018, 'Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain', Science Robotics, vol. 3, no. 19, eaat3818. https://doi.org/10.1126/scirobotics.aat3818
Osborn LE, Dragomir A, Betthauser JL, Hunt CL, Nguyen HH, Kaliki RR et al. Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain. Science Robotics. 2018 Jun 27;3(19). eaat3818. https://doi.org/10.1126/scirobotics.aat3818
Osborn, Luke E. ; Dragomir, Andrei ; Betthauser, Joseph L. ; Hunt, Christopher L. ; Nguyen, Harrison H. ; Kaliki, Rahul R. ; Thakor, Nitish V. / Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain. In: Science Robotics. 2018 ; Vol. 3, No. 19.
@article{0b7ff79146ac4b16a6ff4af03f33bb2b,
title = "Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain",
abstract = "The human body is a template for many state-of-the-art prosthetic devices and sensors. Perceptions of touch and pain are fundamental components of our daily lives that convey valuable information about our environment while also providing an element of protection from damage to our bodies. Advances in prosthesis designs and control mechanisms can aid an amputee's ability to regain lost function but often lack meaningful tactile feedback or perception. Through transcutaneous electrical nerve stimulation (TENS) with an amputee, wediscovered and quantified stimulation parameters to elicit innocuous (nonpainful) and noxious (painful) tactile perceptions in the phantom hand. Electroencephalography (EEG) activity in somatosensory regions confirms phantom hand activation during stimulation. We invented a multilayered electronic dermis (e-dermis) with properties based on the behavior of mechanoreceptors and nociceptors to provide neuromorphic tactile information to an amputee. Our biologically inspired e-dermis enables a prosthesis and its user to perceive a continuous spectrum from innocuous to noxious touch through a neuromorphic interface that produces receptor-like spiking neural activity. In a pain detection task (PDT), we show the ability of the prosthesis and amputee to differentiate nonpainful or painful tactile stimuli using sensory feedback and a pain reflex feedback control system. In this work, an amputee can use perceptions of touch and pain to discriminate object curvature, including sharpness. This work demonstrates possibilities for creating a more natural sensation spanning a range of tactile stimuli for prosthetic hands.",
author = "Osborn, {Luke E.} and Andrei Dragomir and Betthauser, {Joseph L.} and Hunt, {Christopher L.} and Nguyen, {Harrison H.} and Kaliki, {Rahul R.} and Thakor, {Nitish V}",
year = "2018",
month = "6",
day = "27",
doi = "10.1126/scirobotics.aat3818",
language = "English (US)",
volume = "3",
journal = "Science Robotics",
issn = "2470-9476",
publisher = "American Association for the Advancement of Science",
number = "19",

}

TY - JOUR

T1 - Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain

AU - Osborn, Luke E.

AU - Dragomir, Andrei

AU - Betthauser, Joseph L.

AU - Hunt, Christopher L.

AU - Nguyen, Harrison H.

AU - Kaliki, Rahul R.

AU - Thakor, Nitish V

PY - 2018/6/27

Y1 - 2018/6/27

N2 - The human body is a template for many state-of-the-art prosthetic devices and sensors. Perceptions of touch and pain are fundamental components of our daily lives that convey valuable information about our environment while also providing an element of protection from damage to our bodies. Advances in prosthesis designs and control mechanisms can aid an amputee's ability to regain lost function but often lack meaningful tactile feedback or perception. Through transcutaneous electrical nerve stimulation (TENS) with an amputee, wediscovered and quantified stimulation parameters to elicit innocuous (nonpainful) and noxious (painful) tactile perceptions in the phantom hand. Electroencephalography (EEG) activity in somatosensory regions confirms phantom hand activation during stimulation. We invented a multilayered electronic dermis (e-dermis) with properties based on the behavior of mechanoreceptors and nociceptors to provide neuromorphic tactile information to an amputee. Our biologically inspired e-dermis enables a prosthesis and its user to perceive a continuous spectrum from innocuous to noxious touch through a neuromorphic interface that produces receptor-like spiking neural activity. In a pain detection task (PDT), we show the ability of the prosthesis and amputee to differentiate nonpainful or painful tactile stimuli using sensory feedback and a pain reflex feedback control system. In this work, an amputee can use perceptions of touch and pain to discriminate object curvature, including sharpness. This work demonstrates possibilities for creating a more natural sensation spanning a range of tactile stimuli for prosthetic hands.

AB - The human body is a template for many state-of-the-art prosthetic devices and sensors. Perceptions of touch and pain are fundamental components of our daily lives that convey valuable information about our environment while also providing an element of protection from damage to our bodies. Advances in prosthesis designs and control mechanisms can aid an amputee's ability to regain lost function but often lack meaningful tactile feedback or perception. Through transcutaneous electrical nerve stimulation (TENS) with an amputee, wediscovered and quantified stimulation parameters to elicit innocuous (nonpainful) and noxious (painful) tactile perceptions in the phantom hand. Electroencephalography (EEG) activity in somatosensory regions confirms phantom hand activation during stimulation. We invented a multilayered electronic dermis (e-dermis) with properties based on the behavior of mechanoreceptors and nociceptors to provide neuromorphic tactile information to an amputee. Our biologically inspired e-dermis enables a prosthesis and its user to perceive a continuous spectrum from innocuous to noxious touch through a neuromorphic interface that produces receptor-like spiking neural activity. In a pain detection task (PDT), we show the ability of the prosthesis and amputee to differentiate nonpainful or painful tactile stimuli using sensory feedback and a pain reflex feedback control system. In this work, an amputee can use perceptions of touch and pain to discriminate object curvature, including sharpness. This work demonstrates possibilities for creating a more natural sensation spanning a range of tactile stimuli for prosthetic hands.

UR - http://www.scopus.com/inward/record.url?scp=85051590835&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85051590835&partnerID=8YFLogxK

U2 - 10.1126/scirobotics.aat3818

DO - 10.1126/scirobotics.aat3818

M3 - Article

AN - SCOPUS:85051590835

VL - 3

JO - Science Robotics

JF - Science Robotics

SN - 2470-9476

IS - 19

M1 - eaat3818

ER -