Prostatic ductal adenocarcinoma: A mini review

Research output: Contribution to journalArticle

Abstract

Prostatic ductal adenocarcinomas may arise either in large primary periurethral prostatic ducts or in the peripheral prostatic ducts. Ductal adenocarcinomas are composed of tall columnar cells arranged in cribriform, papillary, solid, single glands, and PIN-like patterns. Other than the prostatic intraepithelial neoplasia (PIN)-like ductal pattern, which behaves like Gleason pattern 3, ductal adenocarcinoma is comparable to Gleason pattern 4 prostate cancer. Ductal adenocarcinoma can have a patchy basal cell layer and typically expresses prostate-specific antigen (PSA) immunohistochemically. Mimickers of ductal adenocarcinoma include prostatic urethral polyps, hyperplastic benign prostate glands, high-grade PIN, colorectal adenocarcinoma, and papillary urothelial carcinoma.

Original languageEnglish (US)
Pages (from-to)82-85
Number of pages4
JournalMedical Principles and Practice
Volume19
Issue number1
DOIs
StatePublished - Jan 2009

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Adenocarcinoma
Prostatic Intraepithelial Neoplasia
Papillary Carcinoma
Prostate-Specific Antigen
Polyps
Prostate
Prostatic Neoplasms

Keywords

  • Ductal adenocarcinoma
  • Gleason grade
  • Prostate adenocarcinoma

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Prostatic ductal adenocarcinoma : A mini review. / Epstein, Jonathan Ira.

In: Medical Principles and Practice, Vol. 19, No. 1, 01.2009, p. 82-85.

Research output: Contribution to journalArticle

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