Prostate brachytherapy seed localization with Gaussian blurring and camera self-calibration

Junghoon Lee, Xiaofeng Liu, Jerry L. Prince, Gabor Fichtinger

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A tomosynthesis-based prostate brachytherapy seed localization method is described. Gaussian-blurred images are computed from a limited number of X-ray images, and a 3-D volume is reconstructed by backprojection. Candidate seed locations are extracted from the reconstructed volume and false positive seeds are removed by optimizing a local cost function. In case where the estimated pose error is large, a self-calibration process corrects the estimation error of the intrinsic camera parameters and the translation of the pose in order to improve the reconstruction. Simulation and phantom experiment results imply that the implanted seed locations can be estimated from four or five images depending on the number of seeds. The algorithm was also validated using patient data, successfully localizing the implanted seeds.

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - MICCAI 2008 - 11th International Conference, Proceedings
PublisherSpringer Verlag
Pages636-643
Number of pages8
EditionPART 2
ISBN (Print)3540859896, 9783540859895
DOIs
StatePublished - 2008
Event11th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2008 - New York, NY, United States
Duration: Sep 6 2008Sep 10 2008

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume5242 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other11th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2008
Country/TerritoryUnited States
CityNew York, NY
Period9/6/089/10/08

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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