Propionibacterium as a cause of postneurosurgical infection in patients with dural allografts: Report of three cases

George Jallo, Maxim Koslow, Bruce A. Hanna, Loretta A. Carson

Research output: Contribution to journalArticle

Abstract

OBJECTIVE AND IMPORTANCE: Although Propionibacterium acnes is a common inhabitant of human skin, it is an uncommon pathogen in postoperative infections. We report three cases of postoperative wound infection/osteomyelitis caused by P. acnes. CLINICAL PRESENTATION: Three patients underwent craniotomy for a supratentorial meningioma and had a dural allograft at the time of closure. The patients presented several weeks after surgery with clinical evidence of a wound infection. INTERVENTION: All patients were diagnosed with P. acnes infection and treated for this pathogen with appropriate antibiotics. The bone flap was removed in two patients. After antibiotic therapy, all patients demonstrated no further evidence of infection. CONCLUSION: To our knowledge, this is the first published report of P. acnes infection in patients with a dural substitute. The source of infection cannot be confidently ascertained; however, two patients had strains of P. acnes from one brand of graft, which were indistinguishable by pulsed field gel electrophoresis typing.

Original languageEnglish (US)
Pages (from-to)1138-1141
Number of pages4
JournalNeurosurgery
Volume44
Issue number5
DOIs
StatePublished - May 1999
Externally publishedYes

Fingerprint

Propionibacterium
Propionibacterium acnes
Allografts
Infection
Anti-Bacterial Agents
Surgical Wound Infection
Craniotomy
Pulsed Field Gel Electrophoresis
Meningioma
Wound Infection
Osteomyelitis
Transplants
Bone and Bones
Skin

Keywords

  • Craniotomy
  • Dural graft
  • Infection
  • Osteomyelitis
  • Propionibacterium

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Propionibacterium as a cause of postneurosurgical infection in patients with dural allografts : Report of three cases. / Jallo, George; Koslow, Maxim; Hanna, Bruce A.; Carson, Loretta A.

In: Neurosurgery, Vol. 44, No. 5, 05.1999, p. 1138-1141.

Research output: Contribution to journalArticle

Jallo, George ; Koslow, Maxim ; Hanna, Bruce A. ; Carson, Loretta A. / Propionibacterium as a cause of postneurosurgical infection in patients with dural allografts : Report of three cases. In: Neurosurgery. 1999 ; Vol. 44, No. 5. pp. 1138-1141.
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