PROPERTIES AND METABOLISM OF SOLUBLE LIPOPROTEINS CONTAINING CHOLINE AND ETHANOLAMINE PHOSPHOLIPIDS IN RAT BRAIN

Joyce A. Benjamins, G. M. McKhann

Research output: Contribution to journalArticle

Abstract

Abstract— Choline and ethanolamine phospholipids in the 105,000 g supernatant fraction of rat brain exhibited density and electrophoretic properties consistent with their binding to protein. About 40% of these two phospholipids were bound to soluble lipoproteins, whereas the remainder appeared to be associated with particulate complexes. Following intracranial injection of [2‐3H]glycerol, the specific radioactivities of the choline and ethanolamine phospholipids in the supernatant fraction were higher than those in the microsomal fraction at all time points examined, from 15 min to 12 h after injection. The properties of cytoplasmic lipoproteins containing choline and ethanolamine phospholipids have been compared with those which we have previously described containing sulphatide.

Original languageEnglish (US)
Pages (from-to)1121-1129
Number of pages9
JournalJournal of Neurochemistry
Volume20
Issue number4
DOIs
StatePublished - Apr 1973

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

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