Propagation and primary isolation of papovavirus JC in epithelial cells derived from human urine

A. M. Beckmann, K. V. Shah, B. L. Padgett

Research output: Contribution to journalArticle

Abstract

Human papovavirus JC, previously passaged in amnion cells or in primary human fetal glial cells, replicated efficiently in urine-derived epithelial cells. Primary isolation of the virus from brain extracts was possible in urine-derived cells, but these cells were not as sensitive as primary human fetal glial cells for this purpose. Primary isolations of human papovavirus JC from urine sediments of renal transplant patients were made in urine-derived cells.

Original languageEnglish (US)
Pages (from-to)774-777
Number of pages4
JournalInfection and immunity
Volume38
Issue number2
DOIs
StatePublished - 1982

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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