Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21

Sarah Derks, Linda J W Bosch, Hanneke E C Niessen, Peter T M Moerkerk, Sandra M. van den Bosch, Beatriz Carvalho, Sandra Mongera, J. Willem Voncken, Gerrit A. Meijer, Adriaan P. de Bruïne, James G. Herman, Manon van Engeland

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