Promising treatments of tomorrow for multiple sclerosis

Daniel M. Harrison, Peter A. Calabresi

Research output: Contribution to journalReview article

Abstract

The therapeutic options for multiple sclerosis are rapidly expanding. What was once seen as a disease with little hope for treatment is now a target of rapid drug development. Current therapies have demonstrated efficacy in limiting the impact of the disease, but none is fully effective in all patients. However, promising new treatments are on the horizon. In this review we will discuss potential novel immunomodulating drugs that are in advanced stages of investigation; these drugs include monoclonal antibodies, chimeric molecules, and oral therapies. The use of hematopoietic stem cells will also be discussed and, in addition, we will look farther ahead at possible novel targets for the development of new immunomodulatory or neuroprotective pharmaceuticals.

Original languageEnglish (US)
Pages (from-to)283-290
Number of pages8
JournalAnnals of Indian Academy of Neurology
Volume12
Issue number4
DOIs
StatePublished - Oct 1 2009

Keywords

  • Drugs
  • Investigational
  • Multiple sclerosis
  • Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

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