In the PDA-TOLERATE trial, persistent (even for several weeks) moderate to large patent ductus arteriosus (PDA) was not associated with an increased risk of BPD when the infant required <10 days of intubation. However, in infants requiring intubation for ≥10 days, prolonged PDA exposure (≥11 days) was associated with an increased risk of moderate/severe BPD.
- bronchopulmonary dysplasia
- patent ductus arteriosus
- premature birth
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health