Proline inhibition of pyrroline-5-carboxylate reductase: Differences in enzymes obtained from animal and tissue culture sources

David Valle, Sylvia J. Downing, James M. Phang

Research output: Contribution to journalArticle

Abstract

Pyrroline-5-carboxylate reductase obtained from several cell lines in culture has been shown to be approximately 50X more sensitive to proline inhibition than enzyme obtained from animal tissue sources. The description of this inhibition and possible causes for the difference between animal and tissue culture pyrroline-5-carboxylate reductase are presented.

Original languageEnglish (US)
Pages (from-to)1418-1424
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume54
Issue number4
DOIs
StatePublished - Oct 15 1973
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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