TY - JOUR
T1 - Proliferative Retinopathy in Sickle Cell Trait
T2 - Report of Seven Cases
AU - Nagpal, Krishan C.
AU - Asdourian, George K.
AU - Patrianakos, Dimitrios
AU - Goldberg, Morton F.
AU - Rabb, Maurice F.
AU - Goldbaum, Michael
AU - Raichand, Motilal
PY - 1977/3
Y1 - 1977/3
N2 - Seven patients had sickle cell trait (hemoglobin AS) and vasoproliferative retinopathy. The retinal abnormalities in these seven patients were indistinguishable from those seen in patients with clinically significant sickling hemoglobinopathies (sickle cell-hemoglobin C disease, hemoglobin S-thalassemia disease, and sickle cell anemia). All seven patients also had some evidence of associated systemic disease such as diabetes, syphilis, tuberculosis, or sarcoidosis. In the presence of an associated systemic disease, marked retinopathy can occur in the ordinarily benign condition of sickle cell trait.
AB - Seven patients had sickle cell trait (hemoglobin AS) and vasoproliferative retinopathy. The retinal abnormalities in these seven patients were indistinguishable from those seen in patients with clinically significant sickling hemoglobinopathies (sickle cell-hemoglobin C disease, hemoglobin S-thalassemia disease, and sickle cell anemia). All seven patients also had some evidence of associated systemic disease such as diabetes, syphilis, tuberculosis, or sarcoidosis. In the presence of an associated systemic disease, marked retinopathy can occur in the ordinarily benign condition of sickle cell trait.
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U2 - 10.1001/archinte.1977.03630150035011
DO - 10.1001/archinte.1977.03630150035011
M3 - Article
C2 - 843150
AN - SCOPUS:84942561476
SN - 0003-9926
VL - 137
SP - 325
EP - 328
JO - Archives of internal medicine
JF - Archives of internal medicine
IS - 3
ER -