Projecting the impact of pre-exposure prophylaxis for HIV prevention in the context of gonorrhea and chlamydia infection

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Pre-exposure prophylaxis (PrEP) is recommended for preventing HIV infection among individuals at high risk, including men who have sex with men (MSM). The synergy of HIV and other sexually transmitted infections (STIs) including gonorrhea (NG) and chlamydia (CT) can provide a unique opportunity to target populations at highest risk for HIV infection. However, the population-level impact of such programs at current (and improved) levels of STI screening remains uncertain. Applying an agent-based simulation of HIV and NG/CT infection, we explored the impact of NG/CT-targeted PrEP among MSM in Baltimore City. Our results suggest that targeting MSM infected with NG/CT can be an effective means of PrEP delivery. If high levels of STI screening can be achieved at the community level, NG/CT diagnosis may be an important and efficient entry point for PrEP evaluation and delivery; expanding NG/CT screening in conjunction with PrEP can augment this impact even further.

Original languageEnglish (US)
Title of host publication2017 Winter Simulation Conference, WSC 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4590-4591
Number of pages2
VolumePart F134102
ISBN (Electronic)9781538634288
DOIs
StatePublished - Jan 4 2018
Event2017 Winter Simulation Conference, WSC 2017 - Las Vegas, United States
Duration: Dec 3 2017Dec 6 2017

Other

Other2017 Winter Simulation Conference, WSC 2017
CountryUnited States
CityLas Vegas
Period12/3/1712/6/17

ASJC Scopus subject areas

  • Software
  • Modeling and Simulation
  • Computer Science Applications

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    Kasaie, P., Buyon, L., & Dowdy, D. W. (2018). Projecting the impact of pre-exposure prophylaxis for HIV prevention in the context of gonorrhea and chlamydia infection. In 2017 Winter Simulation Conference, WSC 2017 (Vol. Part F134102, pp. 4590-4591). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/WSC.2017.8248219