TY - GEN
T1 - Projecting the impact of pre-exposure prophylaxis for HIV prevention in the context of gonorrhea and chlamydia infection
AU - Kasaie, Parastu
AU - Buyon, Lucas
AU - Dowdy, David W.
N1 - Publisher Copyright:
© 2017 IEEE.
PY - 2017/6/28
Y1 - 2017/6/28
N2 - Pre-exposure prophylaxis (PrEP) is recommended for preventing HIV infection among individuals at high risk, including men who have sex with men (MSM). The synergy of HIV and other sexually transmitted infections (STIs) including gonorrhea (NG) and chlamydia (CT) can provide a unique opportunity to target populations at highest risk for HIV infection. However, the population-level impact of such programs at current (and improved) levels of STI screening remains uncertain. Applying an agent-based simulation of HIV and NG/CT infection, we explored the impact of NG/CT-targeted PrEP among MSM in Baltimore City. Our results suggest that targeting MSM infected with NG/CT can be an effective means of PrEP delivery. If high levels of STI screening can be achieved at the community level, NG/CT diagnosis may be an important and efficient entry point for PrEP evaluation and delivery; expanding NG/CT screening in conjunction with PrEP can augment this impact even further.
AB - Pre-exposure prophylaxis (PrEP) is recommended for preventing HIV infection among individuals at high risk, including men who have sex with men (MSM). The synergy of HIV and other sexually transmitted infections (STIs) including gonorrhea (NG) and chlamydia (CT) can provide a unique opportunity to target populations at highest risk for HIV infection. However, the population-level impact of such programs at current (and improved) levels of STI screening remains uncertain. Applying an agent-based simulation of HIV and NG/CT infection, we explored the impact of NG/CT-targeted PrEP among MSM in Baltimore City. Our results suggest that targeting MSM infected with NG/CT can be an effective means of PrEP delivery. If high levels of STI screening can be achieved at the community level, NG/CT diagnosis may be an important and efficient entry point for PrEP evaluation and delivery; expanding NG/CT screening in conjunction with PrEP can augment this impact even further.
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U2 - 10.1109/WSC.2017.8248219
DO - 10.1109/WSC.2017.8248219
M3 - Conference contribution
AN - SCOPUS:85044504746
T3 - Proceedings - Winter Simulation Conference
SP - 4590
EP - 4591
BT - 2017 Winter Simulation Conference, WSC 2017
A2 - Chan, Victor
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2017 Winter Simulation Conference, WSC 2017
Y2 - 3 December 2017 through 6 December 2017
ER -