Progressive EPR imaging with adaptive projection acquisition

Yuanmu Deng, Periannan Kuppusamy, Jay L. Zweier

Research output: Contribution to journalArticle

Abstract

Continuous wave electron paramagnetic resonance imaging (EPRI) of living biological systems requires rapid acquisition and visualization of free radical images. In the commonly used multiple-stage back-projection image reconstruction algorithm, the EPR image cannot be reconstructed until a complete set of projections is collected. If the data acquisition is incomplete, the previously acquired incomplete data set is no longer useful. In this work, a 3-dimensional progressive EPRI technique was implemented based on inverse Radon transform in which a 3-dimensional EPR image is acquired and reconstructed gradually from low resolution to high resolution. An adaptive data acquisition strategy is proposed to determine the significance of projections and acquire them in an order from the most significant to the least significant. The image acquisition can be terminated at any time if further collection of projections does not improve the image resolution distinctly, providing flexibility to trade image quality with imaging time. The progressive imaging technique was validated using computer simulations as well as imaging experiments. The adaptive acquisition uses 50-70% less projections as compared to the regular acquisition. In conclusion, adaptive data acquisition with progressive image reconstruction should be very useful for the accelerated acquisition and visualization of free radical distribution.

Original languageEnglish (US)
Pages (from-to)177-187
Number of pages11
JournalJournal of Magnetic Resonance
Volume174
Issue number2
DOIs
StatePublished - Jun 2005
Externally publishedYes

Fingerprint

Computer-Assisted Image Processing
Electron Spin Resonance Spectroscopy
Free Radicals
Paramagnetic resonance
acquisition
projection
Imaging techniques
Radon
data acquisition
Data acquisition
Computer Simulation
image reconstruction
Image reconstruction
imaging techniques
free radicals
electron paramagnetic resonance
Visualization
Image acquisition
image resolution
Biological systems

Keywords

  • Adaptive acquisition
  • EPR imaging
  • Free radical
  • Image reconstruction
  • Radon transform
  • Simulation

ASJC Scopus subject areas

  • Molecular Biology
  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Progressive EPR imaging with adaptive projection acquisition. / Deng, Yuanmu; Kuppusamy, Periannan; Zweier, Jay L.

In: Journal of Magnetic Resonance, Vol. 174, No. 2, 06.2005, p. 177-187.

Research output: Contribution to journalArticle

Deng, Yuanmu ; Kuppusamy, Periannan ; Zweier, Jay L. / Progressive EPR imaging with adaptive projection acquisition. In: Journal of Magnetic Resonance. 2005 ; Vol. 174, No. 2. pp. 177-187.
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