Progress in the development of immunotherapy for the treatment of patients with cancer

S. A. Rosenberg

doi:10.1046/j.1365-2796.2001.00911.x

Progress in the development of immunotherapy for the treatment of patients with cancer

S. A. Rosenberg

Research output: Contribution to journal › Article › peer-review

101 Scopus citations

Abstract

Several recent developments have hallmarked progress in tumour immunology and immunotherapy. The use of interleukin-2 (IL-2) in cancer patients demonstrated that an immunological manipulation was capable of mediating the regression of established growing cancers in humans. The identification of the genes encoding cancer antigens and the development of means for effectively immunizing patients against these antigens has opened important new avenues of exploration for the development of effective active and cell-transfer immunotherapies for patients with cancer.

Original language	English (US)
Pages (from-to)	462-475
Number of pages	14
Journal	Journal of Internal Medicine
Volume	250
Issue number	6
DOIs	https://doi.org/10.1046/j.1365-2796.2001.00911.x
State	Published - 2001
Externally published	Yes

Keywords

Antigens
Cancer
Immunotherapy
Interleukin-2
Melanoma

ASJC Scopus subject areas

Internal Medicine

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10.1046/j.1365-2796.2001.00911.x

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abstract = "Several recent developments have hallmarked progress in tumour immunology and immunotherapy. The use of interleukin-2 (IL-2) in cancer patients demonstrated that an immunological manipulation was capable of mediating the regression of established growing cancers in humans. The identification of the genes encoding cancer antigens and the development of means for effectively immunizing patients against these antigens has opened important new avenues of exploration for the development of effective active and cell-transfer immunotherapies for patients with cancer.",

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AB - Several recent developments have hallmarked progress in tumour immunology and immunotherapy. The use of interleukin-2 (IL-2) in cancer patients demonstrated that an immunological manipulation was capable of mediating the regression of established growing cancers in humans. The identification of the genes encoding cancer antigens and the development of means for effectively immunizing patients against these antigens has opened important new avenues of exploration for the development of effective active and cell-transfer immunotherapies for patients with cancer.

KW - Antigens

KW - Cancer

KW - Immunotherapy

KW - Interleukin-2

KW - Melanoma

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Progress in the development of immunotherapy for the treatment of patients with cancer

Abstract

Keywords

ASJC Scopus subject areas

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