Programming events in the regulation of cell proliferation and death

Richard Berges, John Tod Isaacs

Research output: Contribution to journalArticle

Abstract

In developing new and more successful therapies for preventing and treating cancer, it is critical to understand what normally regulates cell proliferation and cell death and what are the specific dysfunctions associated with these regulations in individual cancers. Here we review the programmed series of molecular, cellular, and biochemical events required for a cell's entrance and progression through the proliferative vs death processes as a starting point for such approaches to new therapies.

Original languageEnglish (US)
Pages (from-to)356-361
Number of pages6
JournalClinical Chemistry
Volume39
Issue number2
StatePublished - 1993

Fingerprint

Cell proliferation
Cell death
Cell Death
Cell Proliferation
Neoplasms
Therapeutics

Keywords

  • Apoptosis
  • Cancer
  • Cyclins
  • P34 kinase

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Programming events in the regulation of cell proliferation and death. / Berges, Richard; Isaacs, John Tod.

In: Clinical Chemistry, Vol. 39, No. 2, 1993, p. 356-361.

Research output: Contribution to journalArticle

@article{f3cd669a075446c89a310f71a2c3be88,
title = "Programming events in the regulation of cell proliferation and death",
abstract = "In developing new and more successful therapies for preventing and treating cancer, it is critical to understand what normally regulates cell proliferation and cell death and what are the specific dysfunctions associated with these regulations in individual cancers. Here we review the programmed series of molecular, cellular, and biochemical events required for a cell's entrance and progression through the proliferative vs death processes as a starting point for such approaches to new therapies.",
keywords = "Apoptosis, Cancer, Cyclins, P34 kinase",
author = "Richard Berges and Isaacs, {John Tod}",
year = "1993",
language = "English (US)",
volume = "39",
pages = "356--361",
journal = "Clinical Chemistry",
issn = "0009-9147",
publisher = "American Association for Clinical Chemistry Inc.",
number = "2",

}

TY - JOUR

T1 - Programming events in the regulation of cell proliferation and death

AU - Berges, Richard

AU - Isaacs, John Tod

PY - 1993

Y1 - 1993

N2 - In developing new and more successful therapies for preventing and treating cancer, it is critical to understand what normally regulates cell proliferation and cell death and what are the specific dysfunctions associated with these regulations in individual cancers. Here we review the programmed series of molecular, cellular, and biochemical events required for a cell's entrance and progression through the proliferative vs death processes as a starting point for such approaches to new therapies.

AB - In developing new and more successful therapies for preventing and treating cancer, it is critical to understand what normally regulates cell proliferation and cell death and what are the specific dysfunctions associated with these regulations in individual cancers. Here we review the programmed series of molecular, cellular, and biochemical events required for a cell's entrance and progression through the proliferative vs death processes as a starting point for such approaches to new therapies.

KW - Apoptosis

KW - Cancer

KW - Cyclins

KW - P34 kinase

UR - http://www.scopus.com/inward/record.url?scp=0027461696&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027461696&partnerID=8YFLogxK

M3 - Article

C2 - 8432028

AN - SCOPUS:0027461696

VL - 39

SP - 356

EP - 361

JO - Clinical Chemistry

JF - Clinical Chemistry

SN - 0009-9147

IS - 2

ER -