Programmed subcellular release for studying the dynamics of cell detachment

Bridget Wildt, Denis Wirtz, Peter C. Searson

Research output: Contribution to journalArticle

Abstract

Cell detachment is central to a broad range of physiopathological changes, but there are no quantitative methods to study this process. Here we report programmed subcellular release, a method for spatially and temporally controlled cellular detachment, and present quantitative results of the detachment dynamics of 3T3 fibroblasts at the subcellular level.

Original languageEnglish (US)
Pages (from-to)211-213
Number of pages3
JournalNature Methods
Volume6
Issue number3
DOIs
StatePublished - Feb 2 2009

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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