Prognostic value of the electroencephalogram in neonatal asphyxia

Gregory Holmes, Jonelle Rowe, James Hafford, Ruth Schmidt, Marcia Testa, Andrew Zimmerman

Research output: Contribution to journalArticle

Abstract

In order to determine whether an EEG early in the course of asphyxia neonatorum is of any more value than the neurological examination in predicting outcome we reviewed case histories of 38 infants with asphyxia neonatorum. The EEG background activity was valuable in predicting outcome. Normal and maturationally delayed EEGs were associated with normal outcomes while low voltage, electrocerebral inactivity and burst suppression EEGs were highly correlated with severe neurological sequelae. Epileptiform activity was not as predictive of outcome as background activity. Although initial normal neurological examinations were associated with normal developmental and neurological outcomes, moderately and severely abnormal infants had more variable courses. A single EEG done early in the course of asphyxia neonatorum is a more sensitive predictor of outcome than the neurological examination.

Original languageEnglish (US)
Pages (from-to)60-72
Number of pages13
JournalElectroencephalography and Clinical Neurophysiology
Volume53
Issue number1
DOIs
StatePublished - 1982
Externally publishedYes

Fingerprint

Asphyxia
Asphyxia Neonatorum
Electroencephalography
Neurologic Examination

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Prognostic value of the electroencephalogram in neonatal asphyxia. / Holmes, Gregory; Rowe, Jonelle; Hafford, James; Schmidt, Ruth; Testa, Marcia; Zimmerman, Andrew.

In: Electroencephalography and Clinical Neurophysiology, Vol. 53, No. 1, 1982, p. 60-72.

Research output: Contribution to journalArticle

Holmes, G, Rowe, J, Hafford, J, Schmidt, R, Testa, M & Zimmerman, A 1982, 'Prognostic value of the electroencephalogram in neonatal asphyxia', Electroencephalography and Clinical Neurophysiology, vol. 53, no. 1, pp. 60-72. https://doi.org/10.1016/0013-4694(82)90106-7
Holmes, Gregory ; Rowe, Jonelle ; Hafford, James ; Schmidt, Ruth ; Testa, Marcia ; Zimmerman, Andrew. / Prognostic value of the electroencephalogram in neonatal asphyxia. In: Electroencephalography and Clinical Neurophysiology. 1982 ; Vol. 53, No. 1. pp. 60-72.
@article{9148d61e0eb347e1999aa8e0ea27dc8c,
title = "Prognostic value of the electroencephalogram in neonatal asphyxia",
abstract = "In order to determine whether an EEG early in the course of asphyxia neonatorum is of any more value than the neurological examination in predicting outcome we reviewed case histories of 38 infants with asphyxia neonatorum. The EEG background activity was valuable in predicting outcome. Normal and maturationally delayed EEGs were associated with normal outcomes while low voltage, electrocerebral inactivity and burst suppression EEGs were highly correlated with severe neurological sequelae. Epileptiform activity was not as predictive of outcome as background activity. Although initial normal neurological examinations were associated with normal developmental and neurological outcomes, moderately and severely abnormal infants had more variable courses. A single EEG done early in the course of asphyxia neonatorum is a more sensitive predictor of outcome than the neurological examination.",
author = "Gregory Holmes and Jonelle Rowe and James Hafford and Ruth Schmidt and Marcia Testa and Andrew Zimmerman",
year = "1982",
doi = "10.1016/0013-4694(82)90106-7",
language = "English (US)",
volume = "53",
pages = "60--72",
journal = "Electroencephalography and Clinical Neurophysiology",
issn = "0013-4694",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - Prognostic value of the electroencephalogram in neonatal asphyxia

AU - Holmes, Gregory

AU - Rowe, Jonelle

AU - Hafford, James

AU - Schmidt, Ruth

AU - Testa, Marcia

AU - Zimmerman, Andrew

PY - 1982

Y1 - 1982

N2 - In order to determine whether an EEG early in the course of asphyxia neonatorum is of any more value than the neurological examination in predicting outcome we reviewed case histories of 38 infants with asphyxia neonatorum. The EEG background activity was valuable in predicting outcome. Normal and maturationally delayed EEGs were associated with normal outcomes while low voltage, electrocerebral inactivity and burst suppression EEGs were highly correlated with severe neurological sequelae. Epileptiform activity was not as predictive of outcome as background activity. Although initial normal neurological examinations were associated with normal developmental and neurological outcomes, moderately and severely abnormal infants had more variable courses. A single EEG done early in the course of asphyxia neonatorum is a more sensitive predictor of outcome than the neurological examination.

AB - In order to determine whether an EEG early in the course of asphyxia neonatorum is of any more value than the neurological examination in predicting outcome we reviewed case histories of 38 infants with asphyxia neonatorum. The EEG background activity was valuable in predicting outcome. Normal and maturationally delayed EEGs were associated with normal outcomes while low voltage, electrocerebral inactivity and burst suppression EEGs were highly correlated with severe neurological sequelae. Epileptiform activity was not as predictive of outcome as background activity. Although initial normal neurological examinations were associated with normal developmental and neurological outcomes, moderately and severely abnormal infants had more variable courses. A single EEG done early in the course of asphyxia neonatorum is a more sensitive predictor of outcome than the neurological examination.

UR - http://www.scopus.com/inward/record.url?scp=0020081371&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020081371&partnerID=8YFLogxK

U2 - 10.1016/0013-4694(82)90106-7

DO - 10.1016/0013-4694(82)90106-7

M3 - Article

C2 - 6173201

AN - SCOPUS:0020081371

VL - 53

SP - 60

EP - 72

JO - Electroencephalography and Clinical Neurophysiology

JF - Electroencephalography and Clinical Neurophysiology

SN - 0013-4694

IS - 1

ER -