Abstract
To determine the predictive value and to define prognostic threshold measurements for mean ovarian volume (MOV) in patients undergoing IVF. Prospective cohort analysis. Tertiary care center. Two hundred sixty-seven patients. Transvaginal ultrasound before starting gonadotropins. Number of oocytes retrieved, basal hormone levels, and cycle outcomes. The MOV for the population was 4.78 ± 2.6 cm 3 (range 0.9-21.1 cm 3). The MOV significantly correlated with the majority of prestimulation and poststimulation IVF parameters. Threshold analysis demonstrated a lower pregnancy rate associated with a MOV of 3 (31.6% vs. 55.6%). Threshold analysis revealed a trend toward higher cancellation rate associated with a MOV of 3 (21.1% vs. 7.3%). Although MOV correlated with IVF stimulation parameters, its use as an adjunct in counseling patients during IVF appears to be of limited value. A MOV 3 was associated clinically with a higher cancellation rate (21.1%) and a lower pregnancy rate (31.6%) in those cycles not cancelled. However, these values do not deviate far from the mean national IVF outcome rates. There was no absolute MOV that was predictive of pregnancy outcome or cycle cancellation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 811-815 |
| Number of pages | 5 |
| Journal | Fertility and Sterility |
| Volume | 82 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 2004 |
| Externally published | Yes |
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Keywords
- basal antral follicle count
- cancellation rate
- clinical outcome
- In vitro fertilization
- mean ovarian volume
- ovarian reserve
- ovarian response
- predictive value
- pregnancy
- review
ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Prognostic use of mean ovarian volume in in vitro fertilization cycles : A prospective assessment. / Frattarelli, John L.; Levi, Andrew J.; Miller, Bradley T.; Segars, James.
In: Fertility and Sterility, Vol. 82, No. 4, 10.2004, p. 811-815.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prognostic use of mean ovarian volume in in vitro fertilization cycles
T2 - A prospective assessment
AU - Frattarelli, John L.
AU - Levi, Andrew J.
AU - Miller, Bradley T.
AU - Segars, James
PY - 2004/10
Y1 - 2004/10
N2 - To determine the predictive value and to define prognostic threshold measurements for mean ovarian volume (MOV) in patients undergoing IVF. Prospective cohort analysis. Tertiary care center. Two hundred sixty-seven patients. Transvaginal ultrasound before starting gonadotropins. Number of oocytes retrieved, basal hormone levels, and cycle outcomes. The MOV for the population was 4.78 ± 2.6 cm 3 (range 0.9-21.1 cm 3). The MOV significantly correlated with the majority of prestimulation and poststimulation IVF parameters. Threshold analysis demonstrated a lower pregnancy rate associated with a MOV of 3 (31.6% vs. 55.6%). Threshold analysis revealed a trend toward higher cancellation rate associated with a MOV of 3 (21.1% vs. 7.3%). Although MOV correlated with IVF stimulation parameters, its use as an adjunct in counseling patients during IVF appears to be of limited value. A MOV 3 was associated clinically with a higher cancellation rate (21.1%) and a lower pregnancy rate (31.6%) in those cycles not cancelled. However, these values do not deviate far from the mean national IVF outcome rates. There was no absolute MOV that was predictive of pregnancy outcome or cycle cancellation.
AB - To determine the predictive value and to define prognostic threshold measurements for mean ovarian volume (MOV) in patients undergoing IVF. Prospective cohort analysis. Tertiary care center. Two hundred sixty-seven patients. Transvaginal ultrasound before starting gonadotropins. Number of oocytes retrieved, basal hormone levels, and cycle outcomes. The MOV for the population was 4.78 ± 2.6 cm 3 (range 0.9-21.1 cm 3). The MOV significantly correlated with the majority of prestimulation and poststimulation IVF parameters. Threshold analysis demonstrated a lower pregnancy rate associated with a MOV of 3 (31.6% vs. 55.6%). Threshold analysis revealed a trend toward higher cancellation rate associated with a MOV of 3 (21.1% vs. 7.3%). Although MOV correlated with IVF stimulation parameters, its use as an adjunct in counseling patients during IVF appears to be of limited value. A MOV 3 was associated clinically with a higher cancellation rate (21.1%) and a lower pregnancy rate (31.6%) in those cycles not cancelled. However, these values do not deviate far from the mean national IVF outcome rates. There was no absolute MOV that was predictive of pregnancy outcome or cycle cancellation.
KW - basal antral follicle count
KW - cancellation rate
KW - clinical outcome
KW - In vitro fertilization
KW - mean ovarian volume
KW - ovarian reserve
KW - ovarian response
KW - predictive value
KW - pregnancy
KW - review
UR - http://www.scopus.com/inward/record.url?scp=5144224305&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=5144224305&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2004.02.143
DO - 10.1016/j.fertnstert.2004.02.143
M3 - Article
C2 - 15482752
AN - SCOPUS:5144224305
VL - 82
SP - 811
EP - 815
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 4
ER -