Prognosis of silent ischemia in acute coronary syndromes

Research output: Contribution to journalArticle

Abstract

The acute coronary syndromes are believed to result from rupture of the fibrous cap of an atherosclerotic plaque in a coronary artery with subsequent intraluminal thrombosis. The thrombosis is the result of platelet activation and aggregation; it may cause complete occlusion of the vessel lumen, resulting in myocardial infarction, or cause intermittent or partial occlusion of the vessel lumen, resulting in unstable angina. Treatment of acute coronary syndromes is aimed at the timely reduction of coronary ischemia and the prevention of myocardial necrosis. Over the past 13. years, studies have shown that silent myocardial ischemia is common in patients with stable and unstable angina. Silent ischemia has been correlated with transient abnormalities in myocardial perfusion and function. In this review we shall summarize salient studies of the value of detection of silent ischemia in predicting prognosis in patients with the acute coronary syndromes, unstable angina and myocardial infarction.

Original languageEnglish (US)
Pages (from-to)338-345
Number of pages8
JournalCardiology in the Elderly
Volume3
Issue number5
StatePublished - 1995

Fingerprint

Unstable Angina
Acute Coronary Syndrome
Ischemia
Myocardial Ischemia
Thrombosis
Myocardial Infarction
Stable Angina
Platelet Activation
Atherosclerotic Plaques
Platelet Aggregation
Rupture
Coronary Vessels
Necrosis
Perfusion
Therapeutics

Keywords

  • Ambulatory electrocardiographic monitoring
  • Asymptomatic ischemia
  • Myocardial infarction
  • Prognosis
  • Unstable angina

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Geriatrics and Gerontology

Cite this

Prognosis of silent ischemia in acute coronary syndromes. / Ouyang, Pamela; Post, Wendy S.

In: Cardiology in the Elderly, Vol. 3, No. 5, 1995, p. 338-345.

Research output: Contribution to journalArticle

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