Profiling of Bacteria by Fast Atom Bombardment Mass Spectrometry

D. N. Heller, R. J. Cotter, Catherine Fenselau, O. M. Uy

Research output: Contribution to journalArticlepeer-review

Abstract

Positive and negative Ion fast atom bombardment mass spectra have been obtained from lysed bacteria Introduced without extraction lnto the mass spectrometer. Phospholipids and other polar lipids are found to be selectively desorbed to provide molecular lons consistent with those observed In spectra of pure lipid samples. Three Gram-positive and three Gram-negative bacteria were studied. The anion spectra from these six bacteria are presented and are found to reflect qualitatively their distinctive phospholipid content. Fast atom bombardment mass spectra may serve as an aid In differentiating species.

Original languageEnglish (US)
Pages (from-to)2806-2809
Number of pages4
JournalAnalytical chemistry
Volume59
Issue number23
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Analytical Chemistry

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