Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting

Peter T. Campbell, Christine B. Ambrosone, Reiko Nishihara, Hugo J.W.L. Aerts, Melissa Bondy, Nilanjan Chatterjee, Montserrat Garcia-Closas, Marios Giannakis, Jeffrey A. Golden, Yujing J. Heng, N. Sertac Kip, Jill Koshiol, X. Shirley Liu, Camila M. Lopes-Ramos, Lorelei A. Mucci, Jonathan A. Nowak, Amanda I. Phipps, John Quackenbush, Robert E. Schoen, Lynette M. ShollRulla M. Tamimi, Molin Wang, Matty P. Weijenberg, Catherine J. Wu, Kana Wu, Song Yao, Kun Hsing Yu, Xuehong Zhang, Timothy R. Rebbeck, Shuji Ogino

Research output: Contribution to journalReview article

Abstract

An important premise of epidemiology is that individuals with the same disease share similar underlying etiologies and clinical outcomes. In the past few decades, our knowledge of disease pathogenesis has improved, and disease classification systems have evolved to the point where no complex disease processes are considered homogenous. As a result, pathology and epidemiology have been integrated into the single, unified field of molecular pathological epidemiology (MPE). Advancing integrative molecular and population-level health sciences and addressing the unique research challenges specific to the field of MPE necessitates assembling experts in diverse fields, including epidemiology, pathology, biostatistics, computational biology, bioinformatics, genomics, immunology, and nutritional and environmental sciences. Integrating these seemingly divergent fields can lead to a greater understanding of pathogenic processes. The International MPE Meeting Series fosters discussion that addresses the specific research questions and challenges in this emerging field. The purpose of the meeting series is to: discuss novel methods to integrate pathology and epidemiology; discuss studies that provide pathogenic insights into population impact; and educate next-generation scientists. Herein, we share the proceedings of the Fourth International MPE Meeting, held in Boston, MA, USA, on 30 May–1 June, 2018. Major themes of this meeting included ‘integrated genetic and molecular pathologic epidemiology’, ‘immunology-MPE’, and ‘novel disease phenotyping’. The key priority areas for future research identified by meeting attendees included integration of tumor immunology and cancer disparities into epidemiologic studies, further collaboration between computational and population-level scientists to gain new insight on exposure-disease associations, and future pooling projects of studies with comparable data.

Original languageEnglish (US)
JournalCancer Causes and Control
DOIs
StatePublished - Jan 1 2019

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Molecular Epidemiology
Epidemiology
Allergy and Immunology
Pathology
Computational Biology
Nutritional Sciences
Biostatistics
Population
Genomics
Ecology
Research
Health Status
Epidemiologic Studies
Neoplasms

Keywords

  • Meeting proceedings
  • Meeting report
  • Meeting summary
  • Molecular pathological epidemiology
  • Patho-epidemiology

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting. / Campbell, Peter T.; Ambrosone, Christine B.; Nishihara, Reiko; Aerts, Hugo J.W.L.; Bondy, Melissa; Chatterjee, Nilanjan; Garcia-Closas, Montserrat; Giannakis, Marios; Golden, Jeffrey A.; Heng, Yujing J.; Kip, N. Sertac; Koshiol, Jill; Liu, X. Shirley; Lopes-Ramos, Camila M.; Mucci, Lorelei A.; Nowak, Jonathan A.; Phipps, Amanda I.; Quackenbush, John; Schoen, Robert E.; Sholl, Lynette M.; Tamimi, Rulla M.; Wang, Molin; Weijenberg, Matty P.; Wu, Catherine J.; Wu, Kana; Yao, Song; Yu, Kun Hsing; Zhang, Xuehong; Rebbeck, Timothy R.; Ogino, Shuji.

In: Cancer Causes and Control, 01.01.2019.

Research output: Contribution to journalReview article

Campbell, PT, Ambrosone, CB, Nishihara, R, Aerts, HJWL, Bondy, M, Chatterjee, N, Garcia-Closas, M, Giannakis, M, Golden, JA, Heng, YJ, Kip, NS, Koshiol, J, Liu, XS, Lopes-Ramos, CM, Mucci, LA, Nowak, JA, Phipps, AI, Quackenbush, J, Schoen, RE, Sholl, LM, Tamimi, RM, Wang, M, Weijenberg, MP, Wu, CJ, Wu, K, Yao, S, Yu, KH, Zhang, X, Rebbeck, TR & Ogino, S 2019, 'Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting', Cancer Causes and Control. https://doi.org/10.1007/s10552-019-01177-z
Campbell, Peter T. ; Ambrosone, Christine B. ; Nishihara, Reiko ; Aerts, Hugo J.W.L. ; Bondy, Melissa ; Chatterjee, Nilanjan ; Garcia-Closas, Montserrat ; Giannakis, Marios ; Golden, Jeffrey A. ; Heng, Yujing J. ; Kip, N. Sertac ; Koshiol, Jill ; Liu, X. Shirley ; Lopes-Ramos, Camila M. ; Mucci, Lorelei A. ; Nowak, Jonathan A. ; Phipps, Amanda I. ; Quackenbush, John ; Schoen, Robert E. ; Sholl, Lynette M. ; Tamimi, Rulla M. ; Wang, Molin ; Weijenberg, Matty P. ; Wu, Catherine J. ; Wu, Kana ; Yao, Song ; Yu, Kun Hsing ; Zhang, Xuehong ; Rebbeck, Timothy R. ; Ogino, Shuji. / Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting. In: Cancer Causes and Control. 2019.
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abstract = "An important premise of epidemiology is that individuals with the same disease share similar underlying etiologies and clinical outcomes. In the past few decades, our knowledge of disease pathogenesis has improved, and disease classification systems have evolved to the point where no complex disease processes are considered homogenous. As a result, pathology and epidemiology have been integrated into the single, unified field of molecular pathological epidemiology (MPE). Advancing integrative molecular and population-level health sciences and addressing the unique research challenges specific to the field of MPE necessitates assembling experts in diverse fields, including epidemiology, pathology, biostatistics, computational biology, bioinformatics, genomics, immunology, and nutritional and environmental sciences. Integrating these seemingly divergent fields can lead to a greater understanding of pathogenic processes. The International MPE Meeting Series fosters discussion that addresses the specific research questions and challenges in this emerging field. The purpose of the meeting series is to: discuss novel methods to integrate pathology and epidemiology; discuss studies that provide pathogenic insights into population impact; and educate next-generation scientists. Herein, we share the proceedings of the Fourth International MPE Meeting, held in Boston, MA, USA, on 30 May–1 June, 2018. Major themes of this meeting included ‘integrated genetic and molecular pathologic epidemiology’, ‘immunology-MPE’, and ‘novel disease phenotyping’. The key priority areas for future research identified by meeting attendees included integration of tumor immunology and cancer disparities into epidemiologic studies, further collaboration between computational and population-level scientists to gain new insight on exposure-disease associations, and future pooling projects of studies with comparable data.",
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AU - Ambrosone, Christine B.

AU - Nishihara, Reiko

AU - Aerts, Hugo J.W.L.

AU - Bondy, Melissa

AU - Chatterjee, Nilanjan

AU - Garcia-Closas, Montserrat

AU - Giannakis, Marios

AU - Golden, Jeffrey A.

AU - Heng, Yujing J.

AU - Kip, N. Sertac

AU - Koshiol, Jill

AU - Liu, X. Shirley

AU - Lopes-Ramos, Camila M.

AU - Mucci, Lorelei A.

AU - Nowak, Jonathan A.

AU - Phipps, Amanda I.

AU - Quackenbush, John

AU - Schoen, Robert E.

AU - Sholl, Lynette M.

AU - Tamimi, Rulla M.

AU - Wang, Molin

AU - Weijenberg, Matty P.

AU - Wu, Catherine J.

AU - Wu, Kana

AU - Yao, Song

AU - Yu, Kun Hsing

AU - Zhang, Xuehong

AU - Rebbeck, Timothy R.

AU - Ogino, Shuji

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N2 - An important premise of epidemiology is that individuals with the same disease share similar underlying etiologies and clinical outcomes. In the past few decades, our knowledge of disease pathogenesis has improved, and disease classification systems have evolved to the point where no complex disease processes are considered homogenous. As a result, pathology and epidemiology have been integrated into the single, unified field of molecular pathological epidemiology (MPE). Advancing integrative molecular and population-level health sciences and addressing the unique research challenges specific to the field of MPE necessitates assembling experts in diverse fields, including epidemiology, pathology, biostatistics, computational biology, bioinformatics, genomics, immunology, and nutritional and environmental sciences. Integrating these seemingly divergent fields can lead to a greater understanding of pathogenic processes. The International MPE Meeting Series fosters discussion that addresses the specific research questions and challenges in this emerging field. The purpose of the meeting series is to: discuss novel methods to integrate pathology and epidemiology; discuss studies that provide pathogenic insights into population impact; and educate next-generation scientists. Herein, we share the proceedings of the Fourth International MPE Meeting, held in Boston, MA, USA, on 30 May–1 June, 2018. Major themes of this meeting included ‘integrated genetic and molecular pathologic epidemiology’, ‘immunology-MPE’, and ‘novel disease phenotyping’. The key priority areas for future research identified by meeting attendees included integration of tumor immunology and cancer disparities into epidemiologic studies, further collaboration between computational and population-level scientists to gain new insight on exposure-disease associations, and future pooling projects of studies with comparable data.

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