TY - JOUR
T1 - Problems with Lithium as Treatment for Inappropriate A.D.H Secretion
AU - Hendler, Nelson
AU - Uematsu, Sumio
AU - Long, Donlin M.
AU - Allen, George
PY - 1976/2/19
Y1 - 1976/2/19
N2 - To the Editor: A recent article by Drs. De Troyer and Demanet (N Engl J Med 293:915, 1975) reported the successful long-term treatment of the syndrome of inappropriate secretion of antidiuretic hormone, with use of demeclocycline, instead of lithium, which had been reported earlier in the Journal,1thereby avoiding the side effects of lithium. There are other reasons to abstain from lithium use in this syndrome. The earlier article1suggested that during short-term (48 hours) lithium administration for the treatment of inappropriate secretion of antidiuretic hormone, sodium “retention was secondary to the effect of increased aldosterone.” The assumption. . . No extract is available for articles shorter than 400 words.
AB - To the Editor: A recent article by Drs. De Troyer and Demanet (N Engl J Med 293:915, 1975) reported the successful long-term treatment of the syndrome of inappropriate secretion of antidiuretic hormone, with use of demeclocycline, instead of lithium, which had been reported earlier in the Journal,1thereby avoiding the side effects of lithium. There are other reasons to abstain from lithium use in this syndrome. The earlier article1suggested that during short-term (48 hours) lithium administration for the treatment of inappropriate secretion of antidiuretic hormone, sodium “retention was secondary to the effect of increased aldosterone.” The assumption. . . No extract is available for articles shorter than 400 words.
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U2 - 10.1056/NEJM197602192940817
DO - 10.1056/NEJM197602192940817
M3 - Letter
C2 - 1246318
AN - SCOPUS:0017310691
SN - 0028-4793
VL - 294
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 8
ER -